Mitchell W G, Snodgrass S R
Neurology Division, Childrens Hospital of Los Angeles, CA 90054.
Pediatr Neurol. 1985 May-Jun;1(3):151-6. doi: 10.1016/0887-8994(85)90054-2.
This paper reports 26 consecutive cases of cerebral cysticercosis in children, 21 presenting with intraparenchymal mass lesions, two with encephalitic disease, and three with intraventricular (racemous) cysticercosis. The intraparenchymal and encephalitic forms of the disease were benign. Regression of the lesions occurred within four months of diagnosis in all children treated conservatively with antiepileptic drugs, but no antiparasitic drugs. Major morbidity was limited to those patients who were subjected to operative intervention. Intraventricular disease was most malignant; all three patients manifested acute, severely increased intracranial pressure, all required immediate surgical decompression, and one patient died. The apparent overall benign course of intraparenchymal cerebral cysticercosis in children appears not to warrant antiparasitic drug therapy.
本文报告了26例儿童脑囊尾蚴病的连续病例,其中21例表现为脑实质内肿块病变,2例为脑炎型,3例为脑室内(葡萄状)囊尾蚴病。脑实质型和脑炎型疾病为良性。所有接受抗癫痫药物保守治疗但未使用抗寄生虫药物的儿童,病变在诊断后四个月内消退。主要并发症仅限于接受手术干预的患者。脑室内疾病最为凶险;所有3例患者均表现为急性、严重的颅内压升高,均需要立即进行手术减压,1例患者死亡。儿童脑实质内囊尾蚴病明显的总体良性病程似乎无需进行抗寄生虫药物治疗。