Division of Cancer Early Detection, National Cancer Control Institute, National Cancer Center, Goyang, Korea.
Cardio-Cerebrovascular Center, Chonnam National University Hospital, Gwangju, Korea.
J Korean Med Sci. 2024 May 27;39(20):e169. doi: 10.3346/jkms.2024.39.e169.
This research article investigates the age, period, and birth cohort effects on prevalence of obesity in the Korean population, with the goal of identifying key factors to inform effective public health strategies.
We analyzed data from the Korea National Health and Nutrition Examination Survey, spanning 2007-2021, including 35,736 men and 46,756 women. Using the hierarchical age-period-cohort (APC) analysis with cross-classified random effects modeling, we applied multivariable mixed logistic regression to estimate the marginal prevalence of obesity across age, period, and birth cohort, while assessing the interaction between APC and lifestyle and socioeconomic factors.
Our findings reveal an inverted U-shaped age effect on obesity, influenced by smoking history ( for interaction = 0.020) and physical activity (I for interaction < 0.001). The period effect was positive in 2020 and 2021, while negative in 2014 ( for period effect < 0.001). A declining trend in obesity prevalence was observed in birth cohorts from 1980s onward. Notably, disparities in obesity rates among recent birth cohorts have increased in relation to smoking history ( for interaction = 0.020), physical activity ( for interaction < 0.001), and residence ( for interaction = 0.005). Particularly, those born after 1960 were more likely to be obese if they were ex-smokers, physical inactive, or lived in rural areas.
These findings highlight growing disparities in obesity within birth cohorts, underscoring the need for targeted health policies that promote smoking cessation and physical activity, especially in rural areas.
本研究旨在探讨年龄、时期和出生队列效应对韩国人口肥胖患病率的影响,以确定关键因素,为制定有效的公共卫生策略提供信息。
我们分析了 2007 年至 2021 年韩国国家健康与营养检查调查的数据,共纳入 35736 名男性和 46756 名女性。采用分层年龄-时期-队列(APC)分析和交叉分类随机效应模型,应用多变量混合逻辑回归估计肥胖的边缘患病率在年龄、时期和出生队列中的分布,并评估 APC 与生活方式和社会经济因素之间的交互作用。
我们的研究结果显示,肥胖的年龄效应呈倒 U 型,受吸烟史(交互作用 = 0.020)和体力活动(交互作用 < 0.001)的影响。2020 年和 2021 年时期效应为正,而 2014 年时期效应为负(时期效应 < 0.001)。肥胖患病率在 20 世纪 80 年代以后的出生队列中呈下降趋势。值得注意的是,与吸烟史(交互作用 = 0.020)、体力活动(交互作用 < 0.001)和居住地(交互作用 = 0.005)相关的肥胖率在最近出生队列中存在差异。具体而言,如果是曾经吸烟、不活跃或居住在农村地区的人,那么出生于 20 世纪 60 年代以后的人更容易肥胖。
这些发现突显了肥胖在出生队列内的差距不断扩大,强调需要采取有针对性的健康政策,促进戒烟和体力活动,特别是在农村地区。