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蛋白酶：重要性、固定化方案、活性炭作为载体的潜力以及修饰用于固定化的载体的重要性。

Proteases: Importance, Immobilization Protocols, Potential of Activated Carbon as Support, and the Importance of Modifying Supports for Immobilization.

作者信息

Santos Mateus Pereira Flores, de Souza Junior Evaldo Cardozo, Villadóniga Carolina, Vallés Diego, Castro-Sowinski Susana, Bonomo Renata Cristina Ferreira, Veloso Cristiane Martins

机构信息

Programa de Pós-Graduação em Biologia e Biotecnologia de Microrganismos (PPGBBM), Universidade Estadual de Santa Cruz (UESC), Rodovia Jorge Amado, km 16, Ilhéus 45662-900, Bahia, Brazil.

Laboratório de Engenharia de Processos, Universidade Estadual do Sudoeste da Bahia (UESB), BR 415, km 04, s/n, Itapetinga 45700-000, Bahia, Brazil.

出版信息

BioTech (Basel). 2024 Apr 30;13(2):13. doi: 10.3390/biotech13020013.

DOI:10.3390/biotech13020013
PMID:38804295
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11130871/
Abstract

Although enzymes have been used for thousands of years, their application in industrial processes has gained importance since the 20th century due to technological and scientific advances in several areas, including biochemistry [...].

摘要

尽管酶已经被使用了数千年，但由于包括生物化学在内的多个领域的技术和科学进步，自20世纪以来，它们在工业过程中的应用变得越来越重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b220/11130871/8119cc9fd7ae/biotech-13-00013-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b220/11130871/88b3a9330b9e/biotech-13-00013-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b220/11130871/f70427ed0b01/biotech-13-00013-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b220/11130871/8119cc9fd7ae/biotech-13-00013-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b220/11130871/88b3a9330b9e/biotech-13-00013-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b220/11130871/f70427ed0b01/biotech-13-00013-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b220/11130871/8119cc9fd7ae/biotech-13-00013-g003.jpg

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1
Proteases: Importance, Immobilization Protocols, Potential of Activated Carbon as Support, and the Importance of Modifying Supports for Immobilization.蛋白酶：重要性、固定化方案、活性炭作为载体的潜力以及修饰用于固定化的载体的重要性。
BioTech (Basel). 2024 Apr 30;13(2):13. doi: 10.3390/biotech13020013.
2
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本文引用的文献

1
Pepsin immobilization on activated carbon and functionalized with glutaraldehyde and genipin for the synthesis of antioxidant peptides of goat casein.固定化胃蛋白酶在活性炭上，并与戊二醛和京尼平功能化，用于合成羊奶酪蛋白抗氧化肽。
Food Res Int. 2024 Jun;186:114161. doi: 10.1016/j.foodres.2024.114161. Epub 2024 Feb 28.
2
Functionalized activated carbon as support for trypsin immobilization and its application in casein hydrolysis.功能化活性炭作为胰蛋白酶固定化的载体及其在酪蛋白水解中的应用。
Bioprocess Biosyst Eng. 2023 Nov;46(11):1651-1664. doi: 10.1007/s00449-023-02927-9. Epub 2023 Sep 20.
3
Enzyme Immobilization Technologies and Industrial Applications.
酶固定化技术及其工业应用
ACS Omega. 2023 Jan 31;8(6):5184-5196. doi: 10.1021/acsomega.2c07560. eCollection 2023 Feb 14.
4
Enzyme immobilization on biomass-derived carbon materials as a sustainable approach towards environmental applications.酶固定在生物量衍生的碳材料上作为一种环境应用的可持续方法。
Chemosphere. 2022 Nov;307(Pt 1):135759. doi: 10.1016/j.chemosphere.2022.135759. Epub 2022 Jul 21.
5
A review on the immobilization of pepsin: A Lys-poor enzyme that is unstable at alkaline pH values.关于胃蛋白酶固定化的综述：一种在碱性 pH 值下不稳定的赖氨酸贫乏的酶。
Int J Biol Macromol. 2022 Jun 15;210:682-702. doi: 10.1016/j.ijbiomac.2022.04.224. Epub 2022 May 1.
6
Pepsin immobilization: Influence of carbon support functionalization.胃蛋白酶固定化：碳载体功能化的影响
Int J Biol Macromol. 2022 Apr 1;203:67-79. doi: 10.1016/j.ijbiomac.2022.01.135. Epub 2022 Jan 26.
7
Immobilization of papain: A review.木瓜蛋白酶固定化：综述。
Int J Biol Macromol. 2021 Oct 1;188:94-113. doi: 10.1016/j.ijbiomac.2021.08.016. Epub 2021 Aug 8.
8
Biotechnological Applications of Proteases in Food Technology.蛋白酶在食品技术中的生物技术应用。
Compr Rev Food Sci Food Saf. 2018 Mar;17(2):412-436. doi: 10.1111/1541-4337.12326. Epub 2018 Jan 19.
9
Improved immobilization of lipase from Thermomyces lanuginosus on a new chitosan-based heterofunctional support: Mixed ion exchange plus hydrophobic interactions.新型壳聚糖基杂化载体上固定化毛壳霉脂肪酶：混合离子交换与疏水相互作用。
Int J Biol Macromol. 2020 Nov 15;163:550-561. doi: 10.1016/j.ijbiomac.2020.07.021. Epub 2020 Jul 6.
10
Hydrolysis of casein from different sources by immobilized trypsin on biochar: Effect of immobilization method.不同来源的酪蛋白在生物炭固定化胰蛋白酶作用下的水解：固定化方法的影响。
J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Jun 1;1146:122124. doi: 10.1016/j.jchromb.2020.122124. Epub 2020 Apr 21.