Department of Respiratory and Critical Care Medicine, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215000, China.
Adv Respir Med. 2024 Apr 28;92(3):190-201. doi: 10.3390/arm92030020.
Sarcoidosis is a multisystem granulomatous disease of an unknown aetiology. It can exist in many organs. Pulmonary and intrathoracic lymph nodes are most commonly involved. Lung sarcoidosis is uncommon in Asia. However, due to the large population of our country and the development of bronchoscopy, percutaneous lung puncture, and other medical technologies, the number of pulmonary sarcoidosis patients is on the rise. Pulmonary sarcoidosis patients have no obvious symptoms in the early stage, and the clinical manifestations in the later stage may vary from person to person. Eventually, the disease progresses to life-threatening pulmonary fibrosis. Therefore, patients with pulmonary sarcoidosis should receive a timely diagnosis. In recent years, the imaging features and serologic biomarkers of pulmonary sarcoidosis have been continuously studied. The diagnostic value of imaging and serologic biomarkers for pulmonary sarcoidosis is summarized below.
结节病是一种病因不明的多系统肉芽肿性疾病。它可以存在于许多器官中。肺部和胸内淋巴结最常受累。亚洲的肺结节病并不常见。然而，由于我国人口众多，以及支气管镜、经皮肺穿刺等医疗技术的发展，肺结节病患者的数量正在上升。肺结节病患者在早期没有明显症状，晚期的临床表现因人而异。最终，疾病进展为危及生命的肺纤维化。因此，肺结节病患者应及时诊断。近年来，肺结节病的影像学特征和血清学标志物不断得到研究。现将影像学和血清学标志物对肺结节病的诊断价值总结如下。
