Dehaven C B, Hurst J M, Branson R D
Crit Care Med. 1985 Jan;13(1):46-8. doi: 10.1097/00003246-198501000-00012.
Twenty-seven surgical patients who developed post-extubation hypoxemia unresponsive to routine respiration therapy (incentive spirometry and chest physical therapy) received continuous positive airway pressure (CPAP) delivered through a mask at an inspired oxygen fraction (FIO2) of 0.45. All patients responded with an increased PaO2 and achieved a PaO2/FIO2 ratio of at least 300 with a mean CPAP of 8.3 +/- 2.8 cm H2O. Mean duration of treatment was 23 +/- 14 h. Two (7%) patients required reintubation, one for control of excessive secretions and the other for persistent Pseudomonas pneumonia. Mask CPAP was an effective treatment for postextubation hypoxemia in this group of surgical patients.
27名外科手术患者在拔管后出现低氧血症，对常规呼吸治疗（激励肺活量测定和胸部物理治疗）无反应，他们通过面罩接受持续气道正压通气（CPAP），吸入氧分数（FIO2）为0.45。所有患者的动脉血氧分压（PaO2）均升高，平均CPAP为8.3±2.8 cm H2O时，PaO2/FIO2比值至少达到300。平均治疗持续时间为23±14小时。两名（7%）患者需要重新插管，一名是为了控制过多分泌物，另一名是因为持续性铜绿假单胞菌肺炎。面罩CPAP是治疗这组外科手术患者拔管后低氧血症的有效方法。
