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生活质量指标变化作为评估耳鼻喉草药疗效的一种方法的临床意义。

CLINICAL SIGNIFICANCE OF CHANGES IN QUALITY OF LIFE INDICATORS AS A METHOD FOR ASSESSING THE EFFECTIVENESS OF ENT HERBAL REMEDIES.

机构信息

1Department of ENT Diseases, Yerevan State Medical University, Armenia.

2Otorhinolaryngology Department, Yerevan State Medical University, Armenia.

出版信息

Georgian Med News. 2024 Mar(348):109-116.

PMID:38807403
Abstract

Ear, nose, and throat (ENT) diseases cause major disruption in patients' daily lives. Self-medication with conventional and herbal drugs are common in ENT patients. Recent studies reported that the ENT patients' self-medication with conventional medication ranged from 79.1-83.0%. It is also reported that the rate of herbal drug utilization among ENT patients ranges from 2-63% in different nations. The research aims to evaluate the effectiveness of "Herbanoma" as a Phyto preparation for ENT diseases according to the prognostic clinical significance of changes in quality-of-life parameters. The study employed the stratified sampling technique to randomly select participants. Five secondary schools of Yerevan were chosen through random selection, followed by the selection of 236 observation units from the selected schools. For the treatment and prevention of diseases of the upper respiratory tract, we used the herbal inhalation mixture "Herbaroma" as an ingredient. The composition of these drops is approved by the Intellectual Property Agency of the Republic of Armenia. SF-36 questionnaire was used to assess the quality of life of adolescents aged 15-17 years who had ENT diseases. The change of the parameters of QL in the experimental group had the greatest clinical significance for the components RP, RE, SF, and Mental Health - MH. The effectiveness of the preventive program was also evaluated according to the main groups of ENT diseases. The clinical significance of the effectiveness of the program for chronic diseases of the nasal cavities was significantly high for almost all components of the quality of life, in particular: Physical health - PH, Mental Health - MH. The program had great effectiveness for this group of ENT diseases. The clinical significance of the effectiveness of prevention programs for chronic inflammatory diseases of the throat was significantly high for the following components of the quality of life: RP, GH, PH, MH. The program has been highly effective for this group of ENT diseases. The clinical significance of the effectiveness of the prevention of chronic inflammatory diseases of the ear was generally assessed as weak. It had reliable average clinical significance for SF, RE, and MH components. Among school-aged children with ENT pathology, the use of the "Herbaroma" drug for prophylactic purposes leads to an improvement in quality-of-life parameters. According to the results of the research, the "Herbaroma" drug had an anti-inflammatory, antiseptic effect, contributed to the reduction of the incidence of acute respiratory viral infections, and the prevention of complications. The use of the relatively safe and effective "Herbaroma" preparation in school conditions should be included in the comprehensive program of preventive measures.

摘要

耳鼻喉(ENT)疾病严重扰乱患者的日常生活。ENT 患者经常自行使用常规药物和草药进行治疗。最近的研究报告称,常规药物的 ENT 患者自我用药率在 79.1-83.0%之间。也有报道称,不同国家 ENT 患者使用草药的比率在 2-63%之间。本研究旨在根据生活质量参数变化的预后临床意义,评估“Herbanoma”作为一种治疗 ENT 疾病的植物制剂的疗效。该研究采用分层抽样技术随机选择参与者。通过随机选择,选择了埃里温的五所中学,然后从选定的学校中选择了 236 个观察单位。为了治疗和预防上呼吸道疾病,我们使用了草药吸入混合物“Herbaroma”作为一种成分。这些滴剂的成分已获得亚美尼亚共和国知识产权局的批准。我们使用 SF-36 问卷评估了患有 ENT 疾病的 15-17 岁青少年的生活质量。实验组参数的变化在 RP、RE、SF 和心理健康 - MH 等成分方面具有最大的临床意义。根据主要的 ENT 疾病组别,还评估了预防计划的有效性。对于鼻腔慢性疾病,该计划对生活质量的几乎所有成分,特别是:身体健康 - PH、心理健康 - MH 都具有显著的高临床效果。该计划对这组 ENT 疾病非常有效。对于慢性咽喉炎症性疾病,预防计划的有效性具有显著的高临床意义,特别是在生活质量的以下成分方面:RP、GH、PH、MH。该计划对这组 ENT 疾病非常有效。预防慢性耳部炎症性疾病的有效性的临床意义通常被评估为较弱。它对 SF、RE 和 MH 成分具有可靠的平均临床意义。在患有 ENT 病理的学龄儿童中,预防性使用“Herbaroma”药物可改善生活质量参数。根据研究结果,“Herbaroma”药物具有抗炎、防腐作用,有助于降低急性呼吸道病毒感染的发生率,并预防并发症。在学校环境中使用相对安全有效的“Herbaroma”制剂应包含在综合预防措施方案中。

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