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苹果口服免疫疗法治疗花粉食物过敏综合征的疗效

Outcomes of apple oral immunotherapy in pollen food allergy syndrome.

作者信息

Dijkema Desie, Ruitenbeek Mirte C, Weerstand-Noor Kirsten, Oude Elberink Hanneke N G, van de Ven Annick A J M

机构信息

Department of Dietetics, University Medical Centre Groningen, Groningen, The Netherlands.

Department of Internal Medicine, Division of Allergology, University Medical Centre Groningen, Groningen, The Netherlands.

出版信息

J Allergy Clin Immunol Glob. 2024 May 1;3(3):100271. doi: 10.1016/j.jacig.2024.100271. eCollection 2024 Aug.

DOI:10.1016/j.jacig.2024.100271
PMID:38808317
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11131049/
Abstract

Oral immunotherapy with apple induces tolerance for an entire apple (128 g) in patients with pollen food allergy syndrome who previously tolerated a median amount of 4 g of apple.

摘要

对于花粉食物过敏综合征患者，若其先前能耐受的苹果中位剂量为4克，那么用苹果进行口服免疫疗法可使他们对整个苹果（128克）产生耐受性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/801a/11131049/820133dd5d17/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/801a/11131049/820133dd5d17/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/801a/11131049/820133dd5d17/gr1.jpg

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本文引用的文献

1
Oral birch pollen immunotherapy with apples: Results of a phase II clinical pilot study.口服桦树花粉免疫治疗与苹果：一项 II 期临床试点研究结果。
Immun Inflamm Dis. 2021 Jun;9(2):503-511. doi: 10.1002/iid3.410. Epub 2021 Feb 23.
2
The Effect of Birch Pollen Immunotherapy on Apple and rMal d 1 Challenges in Adults with Apple Allergy.桦树花粉免疫治疗对苹果和 rMal d 1 激发试验在苹果过敏成人中的作用。
Nutrients. 2020 Feb 18;12(2):519. doi: 10.3390/nu12020519.
3
Yogurt and other fermented foods as sources of health-promoting bacteria.酸奶和其他发酵食品作为促进健康的细菌来源。
Nutr Rev. 2018 Dec 1;76(Suppl 1):4-15. doi: 10.1093/nutrit/nuy056.
4
Eosinophilic esophagitis and symptoms possibly related to eosinophilic esophagitis in oral immunotherapy.嗜酸性粒细胞性食管炎及口服免疫治疗中可能与嗜酸性粒细胞性食管炎相关的症状。
Ann Allergy Asthma Immunol. 2018 Mar;120(3):237-240.e4. doi: 10.1016/j.anai.2017.11.016. Epub 2018 Feb 1.
5
Measurement of health-related quality of life in adult patients with birch pollen-associated food allergy.桦树花粉相关食物过敏成年患者健康相关生活质量的测量
J Dtsch Dermatol Ges. 2016 Apr;14(4):397-404. doi: 10.1111/ddg.12731. Epub 2016 Feb 10.
6
Continuous apple consumption induces oral tolerance in birch-pollen-associated apple allergy.连续食用苹果可诱导桦树花粉相关苹果过敏的口服耐受。
Allergy. 2012 Feb;67(2):280-5. doi: 10.1111/j.1398-9995.2011.02744.x. Epub 2011 Nov 10.
7
The impact of pollen-related food allergens on pollen allergy.花粉相关食物过敏原对花粉过敏的影响。
Allergy. 2007 Jan;62(1):3-10. doi: 10.1111/j.1398-9995.2006.01258.x.
8
Effects of birch pollen-specific immunotherapy on apple allergy in birch pollen-hypersensitive patients.桦树花粉特异性免疫疗法对桦树花粉过敏患者苹果过敏的影响。
Clin Exp Allergy. 1998 Nov;28(11):1368-73. doi: 10.1046/j.1365-2222.1998.00399.x.