Department of Gastrointestinal Surgery, Harbin Medical University Cancer Hospital, Harbin, China.
J Laparoendosc Adv Surg Tech A. 2024 Sep;34(9):814-821. doi: 10.1089/lap.2024.0113. Epub 2024 May 29.
Duodenal stump fistula represents an infrequent but serious complication after laparoscopic radical gastrectomy with Billroth II or Roux-en-Y reconstruction for gastric cancer. The present study was designed to evaluate the effectiveness of laparoscopic double half purse-string sutures plus "8" pattern of stitching for reinforcement of duodenal stump. The data of patients undergoing laparoscopic radical gastrectomy with Billroth II or Roux-en-Y reconstruction were retrospectively analyzed between August 2022 and June 2023. According to the different reinforcement methods of duodenal stump, included patients were subdivided into three groups as follows: Group A, duodenal stump was treated with double half purse-string sutures plus "8" pattern of stitching; Group B, duodenal stump was reinforced by continuous suture using a barbed suture; and Group C, duodenal stump without any additional processing. The incidences of duodenal stump fistula between three groups were documented and compared. Moreover, the independent risk factors associated with duodenal stump fistula were analyzed using the logistic regression analysis. No postoperative duodenal stump fistula occurred in Group A, which was significantly different from Group B and Group C ( = .007). In the multivariate analysis, age (odds ratio [OR], 1.191; 95% confidence interval [CI], 1.088-1.303), body mass index (OR, 0.824; 95% CI, 0.727-0.935), and American Society of Anesthesiologists score (OR, 4.495; 95% CI, 1.264-15.992) were the risk factors for duodenal stump fistula. Double half purse-string sutures plus "8" pattern of suture can be conducted in a relatively short operation period and could prevent the incidence of duodenal stump fistula to some extent.
十二指肠残端瘘是腹腔镜根治性胃切除术(毕罗氏Ⅱ式或 Roux-en-Y 重建)后一种罕见但严重的并发症,用于治疗胃癌。本研究旨在评估腹腔镜双重半荷包缝合加“8”字缝合加强十二指肠残端的有效性。
回顾性分析 2022 年 8 月至 2023 年 6 月期间行腹腔镜根治性胃切除术(毕罗氏Ⅱ式或 Roux-en-Y 重建)的患者资料。根据十二指肠残端不同的加固方法,将患者分为三组:A 组,十二指肠残端采用双重半荷包缝合加“8”字缝合;B 组,采用带刺缝线连续缝合加固;C 组,不做任何额外处理。记录三组患者十二指肠残端瘘的发生率并进行比较。此外,采用 logistic 回归分析分析与十二指肠残端瘘相关的独立危险因素。
A 组无术后十二指肠残端瘘,与 B 组和 C 组比较差异有统计学意义( =.007)。多因素分析显示,年龄(比值比[OR],1.191;95%置信区间[CI],1.088-1.303)、体质量指数(OR,0.824;95%CI,0.727-0.935)和美国麻醉医师协会评分(OR,4.495;95%CI,1.264-15.992)是十二指肠残端瘘的危险因素。
双重半荷包缝合加“8”字缝合可以在相对较短的手术时间内进行,在一定程度上可以预防十二指肠残端瘘的发生。