Liu Wei, Zheng Fei, Ma Chaofan, Xu Wei, Chen Yunfei, Sha Jingjie
Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, Southeast University, Nanjing 211189, China.
School of Mechanical Engineering, Southeast University, Nanjing 211189, China.
Anal Chem. 2024 Jun 11;96(23):9544-9550. doi: 10.1021/acs.analchem.4c01035. Epub 2024 May 29.
Nanobubbles play an important role in diverse fields, including engineering, medicine, and agriculture. Understanding the characteristics of individual nanobubbles is essential for comprehending fluid dynamics behaviors and advancing nanoscale science across various fields. Here, we report a strategy based on nanopore sensors for characterizing single-digit nanobubbles. We investigated the sizes and diffusion coefficients of nanobubbles at different voltages. Additionally, the finite element simulation and molecular dynamics simulation were introduced to account for counterion concentration variation around nanobubbles in the nanopore. In particular, the differences in stability and surface charge density of nanobubbles under various solution environments have been studied by the ion-stabilized model and the DLVO theory. Additionally, a straightforward method to mitigate nanobubble generation in the bulk for reducing current noise in nanopore sensing was suggested. The results hold significant implications for enhancing the understanding of individual nanobubble characterizations, especially in the nanofluid field.
纳米气泡在包括工程、医学和农业在内的多个领域发挥着重要作用。了解单个纳米气泡的特性对于理解流体动力学行为以及推动各个领域的纳米科学发展至关重要。在此，我们报告了一种基于纳米孔传感器来表征个位数纳米气泡的策略。我们研究了不同电压下纳米气泡的尺寸和扩散系数。此外，引入了有限元模拟和分子动力学模拟来解释纳米孔中纳米气泡周围抗衡离子浓度的变化。特别地，通过离子稳定模型和DLVO理论研究了各种溶液环境下纳米气泡在稳定性和表面电荷密度方面的差异。此外，还提出了一种在本体中减少纳米气泡产生以降低纳米孔传感中电流噪声的直接方法。这些结果对于增进对单个纳米气泡表征的理解具有重要意义，尤其是在纳米流体领域。
