腹腔液中腹膜肿瘤 DNA：腹膜转移检测的新兴工具。
Peritoneal Tumour DNA in Peritoneal Fluid: Emerging Tool for Peritoneal Metastasis Detection.
机构信息
Department of Digestive Surgery, Université Paris Cité, Assistance Publique Hôpitaux de Paris, Georges Pompidou University Hospital, Paris, France.
Pharmacogenomics and Molecular Oncology Unit, Biochemistry Department, Université Paris Cité, Assistance Publique Hôpitaux de Paris, Georges Pompidou University Hospital, Paris, France.
出版信息
J Gastrointest Cancer. 2024 Sep;55(3):1463-1466. doi: 10.1007/s12029-024-01071-1. Epub 2024 May 29.
The prognostic significance of positive peritoneal cytology still varied between cancer types and geographical origin. However, because of the lack of sensitivity of this biomarker, conventional cytology is not routinely performed in every country. Here, we wanted to test a new biomarker, peritoneal tumour DNA, using NGS technique, in order to compare it with the historical one, in patients having peritoneal metastases of gastrointestinal or ovarian cancer.
阳性腹膜细胞学的预后意义在不同癌症类型和地理来源之间仍然存在差异。然而，由于这种生物标志物的敏感性不足，常规细胞学检查并非在每个国家都常规进行。在这里，我们想用 NGS 技术检测一种新的生物标志物，即腹膜肿瘤 DNA，以与历史标志物进行比较，用于患有胃肠道或卵巢癌腹膜转移的患者。
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