Faculty of Public Health, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam.
Department of Epidemiology, Hanoi University of Public Health, Hanoi, Vietnam.
Asian Pac J Cancer Prev. 2024 May 1;25(5):1725-1735. doi: 10.31557/APJCP.2024.25.5.1725.
Gastrointestinal (GI) cancer burden in Asia is increasing, and Vietnam is no exception. Assessing the affordability of achieving a quality-adjusted life year (QALY) in gastrointestinal cancer patients Vietnam, as well as identifying predictors of willingness to pay (WTP) per QALY, is crucial to decision-making around medical intervention prioritization and performing medical technology assessments for these cancers.
Our study aimed to estimate WTP/QALY gained and associated factors among patients diagnosed with GI cancer at a tertiary hospital in Hue, Vietnam.
A cross-sectional descriptive study, using contingent valuation methodology was conducted among 231 patients at tertiary hospital in 2022. A double limited dichotomous choice and the EQ-5D-5L were utilised to estimate WTP and QALY, respectively. Quantile regression was applied to determine predictors of WTP/QALY.
The mean and median maximum WTP/QALY gained among GI patients was $15,165.6 (42,239.6) and $4,365.6 (IQR: 1,586.5-14,552.0), respectively, which was equal to 3.68 times the 2022 gross domestic product (GDP) per capita in Vietnam. Additionally, cancer severity was found to have a significant impact on WTP per QALY gained, with a higher amount identified among patients with earlier stages of GI cancer. Furthermore, living in an urban dwelling and patients' treatment modalities were significantly associated with WTP/QALY.
Evidence from our study can be used to inform how decision-makers in Vietnam to determine the cost-effectiveness of GI cancer interventions.
亚洲地区的胃肠道（GI）癌症负担正在增加，越南也不例外。评估越南胃肠道癌症患者实现质量调整生命年（QALY）的负担能力，以及确定每 QALY 支付意愿（WTP）的预测因素，对于医疗干预措施的优先级决策以及对这些癌症进行医疗技术评估至关重要。
我们的研究旨在估计在越南 Hue 的一家三级医院诊断为胃肠道癌症的患者的每 QALY 支付意愿（WTP）和相关因素。
2022 年在一家三级医院进行了一项横断面描述性研究，使用了条件价值评估方法。利用双限制二项选择和 EQ-5D-5L 分别估计 WTP 和 QALY。应用分位数回归来确定 WTP/QALY 的预测因素。
胃肠道癌症患者的平均和中位数最大 WTP/QALY 分别为 15165.6 美元（42239.6 越南盾）和 4365.6 美元（IQR：1586.5-14552.0 越南盾），这相当于 2022 年越南人均国内生产总值（GDP）的 3.68 倍。此外，癌症严重程度对每 QALY 获得的 WTP 有显著影响，GI 癌症早期阶段的患者支付意愿更高。此外，居住在城市地区和患者的治疗方式与 WTP/QALY 显著相关。
我们研究的证据可以为越南决策者确定胃肠道癌症干预措施的成本效益提供信息。
