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《2021年菲律宾分化型甲状腺癌诊断与管理临时临床实践指南》执行摘要

An Executive Summary of The Philippine Interim Clinical Practice Guidelines for the Diagnosis and Management of Well Differentiated Thyroid Cancer 2021.

出版信息

Acta Med Philipp. 2024 May 15;58(8):5-30. doi: 10.47895/amp.vi0.6535. eCollection 2024.

DOI:10.47895/amp.vi0.6535
PMID:38812767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11132293/
Abstract

OBJECTIVES

Thyroid cancer is the most common endocrine cancer in the Philippines affecting primarily women in the reproductive age group. Considering the burden of thyroid cancer in the country, the Department of Health (DOH) called for the development of a national clinical practice guideline that would address patient needs, and aid physicians in clinical decision-making while considering therapeutic cost and availability in the local setting. The 2021 guidelines are aimed at providing optimal care to Filipino patients by assisting clinicians in the evaluation of thyroid nodules and management of well differentiated thyroid cancer.

METHODS

A steering committee convened to formulate clinical questions pertaining to the screening and evaluation of thyroid nodules, surgical and post operative management of thyroid cancer, and palliative care for unresectable disease. A technical working group reviewed existing clinical guidelines, retrieved through a systematic literature search, synthesized clinical evidence, and drafted recommendations based on the ADAPTE process of clinical practice guideline development. The consensus panel reviewed evidence summaries and voted on recommendations for the final statements of the clinical practice guidelines.

RESULTS

The guidelines consist of clinical questions and recommendations grouped into six key areas of management of well differentiated thyroid cancer: screening, diagnosis, surgical treatment, post operative management, surveillance, and palliative care.

CONCLUSION

The 2021 guidelines for well differentiated cancer could direct physicians in clinical decision making, and create better outcomes for Filipino patients afflicted with the disease. However, patient management should still be governed by sound clinical judgement and open physician-patient communication.

摘要

目标

甲状腺癌是菲律宾最常见的内分泌癌,主要影响育龄期女性。考虑到该国甲状腺癌的负担,卫生部呼吁制定一项国家临床实践指南,以满足患者需求,并在考虑治疗成本和当地可及性的同时,帮助医生进行临床决策。2021年指南旨在通过协助临床医生评估甲状腺结节和管理分化型甲状腺癌,为菲律宾患者提供最佳护理。

方法

成立了一个指导委员会,以制定与甲状腺结节的筛查和评估、甲状腺癌的手术及术后管理以及不可切除疾病的姑息治疗相关的临床问题。一个技术工作组审查了通过系统文献检索获得的现有临床指南,综合了临床证据,并根据临床实践指南制定的ADAPTE流程起草了建议。共识小组审查了证据摘要,并就临床实践指南最终声明的建议进行了投票。

结果

该指南包括临床问题和建议,分为分化型甲状腺癌管理的六个关键领域:筛查、诊断、手术治疗、术后管理、监测和姑息治疗。

结论

2021年分化型甲状腺癌指南可为医生的临床决策提供指导,并为患有该疾病的菲律宾患者带来更好的治疗效果。然而,患者管理仍应以合理的临床判断和开放的医患沟通为指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fa/11132293/7955e84b40f5/AMP-58-8-6535-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fa/11132293/ccd8163118c0/AMP-58-8-6535-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fa/11132293/ee1a9df9c0e8/AMP-58-8-6535-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fa/11132293/7955e84b40f5/AMP-58-8-6535-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fa/11132293/ccd8163118c0/AMP-58-8-6535-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fa/11132293/ee1a9df9c0e8/AMP-58-8-6535-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27fa/11132293/7955e84b40f5/AMP-58-8-6535-g003.jpg

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