Al Balkhi Abdulrahman, Berro Mohamad, Keieaty Sameh, Youssef Rahaf, Aboud Emad, Shmayyes Nour Alhoda, Fandi Zain, Esmail Anan
Faculty of Medicine, Damascus University, Damascus, Syria.
Pulmonary Department, Faculty of Medicine, Damascus University, Damascus, Syria.
SAGE Open Med Case Rep. 2024 May 28;12:2050313X241257441. doi: 10.1177/2050313X241257441. eCollection 2024.
Behçet's disease is a chronic systemic inflammatory vasculitis of unknown etiology. It is characterized by recurrent episodes of oral aphthous ulcers, genital ulcers, skin lesions, ocular lesions, and other manifestations. This disease affects many organs and systems, showing a wide range of clinical features. Although pulmonary artery involvement is not common in Behçet's disease, its presence carries a substantial risk of mortality. This report provides a detailed history of a 25-year-old male who was admitted with productive cough, hemoptysis, dyspnea on minimal exertion, fever, and chest pain. He had recurrent orchitis and epididymitis for 7 years, as well as oral and genital ulcers and severe headache. Clinical examination revealed decreased breath sounds at the right middle lung. Thoracic computed tomography angiography confirmed multiple pulmonary artery aneurysms bilaterally. The patient was diagnosed with Behçet's disease, and immunosuppression therapy was initiated. During follow-up, the patient did not report any complications. This case report underscores the significance for clinicians to consider Behçet's disease as a differential diagnosis in patients presenting with hemoptysis and a history of orchitis and epididymitis, given that Behçet's disease rarely causes pulmonary artery aneurysms.
白塞病是一种病因不明的慢性全身性炎症性血管炎。其特征为复发性口腔溃疡、生殖器溃疡、皮肤病变、眼部病变及其他表现。该病累及多个器官和系统,呈现出广泛的临床特征。尽管肺动脉受累在白塞病中并不常见,但其存在会带来相当大的死亡风险。本报告详细介绍了一名25岁男性患者的病史,该患者因咳痰、咯血、轻微活动即出现呼吸困难、发热及胸痛入院。他有7年复发性睾丸炎和附睾炎病史,还有口腔溃疡、生殖器溃疡及严重头痛。临床检查发现右中肺呼吸音减弱。胸部计算机断层扫描血管造影证实双侧多发肺动脉瘤。该患者被诊断为白塞病,并开始进行免疫抑制治疗。在随访期间,患者未报告任何并发症。鉴于白塞病很少引起肺动脉瘤,本病例报告强调了临床医生在面对咯血且有睾丸炎和附睾炎病史的患者时,将白塞病作为鉴别诊断的重要性。