Cruz-Jiménez Lizeth, Barrientos-Gutiérrez Inti, Vidaña-Pérez Dèsirée, Gallegos-Carrillo Katia, Arillo-Santillán Edna, Rodríguez-Bolaños Rosibel, Hardin James W, Kim Minji, Thrasher James F
Department of Health Promotion, Education and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, United States.
Evaluation and Survey Research Center, National Institute of Public Health, Cuernavaca, Mexico.
Tob Induc Dis. 2024 May 29;22. doi: 10.18332/tid/187576. eCollection 2024.
Heated tobacco products (HTPs) are promoted as less harmful than cigarettes; nonetheless, whether HTPs help smokers quit is uncertain.
Data from 4067 Mexican adult smokers surveyed longitudinally every four months (November 2019-March 2021) were analyzed. Mixed-effects multinomial models regressed HTP use frequency (no use=reference; monthly; weekly; and daily use) on sociodemographics and tobacco/nicotine-related variables. Among participants who completed at least two surveys (n=2900) over four months, the duration of their longest smoking quit attempt (SQA) between surveys (SQAs: <30 days; ≥30 days; no SQA=reference) was regressed on HTP use frequency, and changes in the number of cigarettes smoked per day were regressed on HTP initiation between surveys, adjusting for covariates.
Consistent predictors of all HTP use frequencies (monthly, weekly, or daily vs no use) were daily smoking >5 cigarettes (ARRR=1.69 [95% CI: 1.12-2.55], 1.88 [95% CI: 1.26-2.81] and 6.46 [95% CI: 3.33-12.52], respectively); e-cigarette use (ARRR =5.68 [95% CI: 3.38-9.53], 6.54 [95% CI: 4.06-10.55] and 2.59 [95% CI: 1.26-5.30]); lower HTP risk perceptions (ARRR=2.12 [95% CI: 1.50-30.00], 2.25 [95% CI: 1.63-3.10] and 2.00 [95% CI: 1.25-3.22]); exposure to HTP information inside (ARRR=2.13 [95% CI: 1.44-3.15], 2.13 [95% CI: 1.49-3.05] and 3.72 [95% CI: 2.28-6.09]) and outside stores (ARRR=2.36 [95% CI: 1.56-3.57], 2.32 [95% CI: 1.65-3.25] and 2.44 [95% CI: 1.41-4.24]) where tobacco is sold; having family (ARRR=2.46 [95% CI: 1.54-3.91], 2.90 [95% CI: 1.93-4.37] and 2.96 [95% CI: 1.52-5.77]) and friends (ARRR=5.78 [95% CI: 3.60-9.30], 4.98 [95% CI: 3.22-7.72] and 6.61 [95% CI: 2.91-15.01]) who use HTPs. HTP use frequency was not associated with quit attempts, except for monthly HTP use predicting SQAs lasting ≥30 days (ARRR=2.12 [95% CI: 1.17-3.85]). Initiation of HTP use was not associated with changes in smoking frequency. Limiting analysis to those who intend to quit smoking also yielded null results.
Among Mexican adult smokers, frequency of HTP use was mostly not associated with either cessation behaviors or changes in cigarette consumption, suggesting that HTPs have limited to no effectiveness for smoking cessation.
加热烟草制品(HTP)被宣传为比香烟危害更小;然而,HTP是否有助于吸烟者戒烟尚不确定。
对4067名墨西哥成年吸烟者的数据进行分析,这些吸烟者每四个月(2019年11月至2021年3月)接受一次纵向调查。混合效应多项模型将HTP使用频率(不使用=参照;每月使用;每周使用;每日使用)与社会人口统计学以及烟草/尼古丁相关变量进行回归分析。在四个月内至少完成两次调查的参与者(n = 2900)中,将他们两次调查之间最长戒烟尝试(SQA)的持续时间(SQA:<30天;≥30天;无SQA =参照)与HTP使用频率进行回归分析,并将两次调查之间每日吸烟量的变化与HTP开始使用情况进行回归分析,同时对协变量进行调整。
所有HTP使用频率(每月、每周或每日使用与不使用相比)的一致预测因素包括:每日吸烟超过5支(调整风险比[ARRR]分别为1.69[95%置信区间:1.12 - 2.55]、1.88[95%置信区间:1.26 - 2.81]和6.46[95%置信区间:3.33 - 12.52]);使用电子烟(ARRR = 5.68[95%置信区间:3.38 - 9.53]、6.54[95%置信区间:4.06 - 10.55]和2.59[95%置信区间:1.26 - 5.30]);对HTP较低的风险认知(ARRR = 2.12[95%置信区间:1.50 - 30.00]、2.25[95%置信区间:1.63 - 3.10]和2.00[95%置信区间:1.25 - 3.22]);在烟草销售店内(ARRR = 2.13[95%置信区间:1.44 - 3.15]、2.13[95%置信区间:1.49 - 3.05]和3.72[95%置信区间:2.28 - 6.09])和店外(ARRR = 2.36[95%置信区间:1.56 - 3.57]、2.32[95%置信区间:1.65 - 3.25]和2.44[95%置信区间:1.41 - 4.24])接触到HTP信息;有使用HTP的家人(ARRR = 2.46[95%置信区间:1.54 - 3.91]、2.90[95%置信区间:1.93 - 4.37]和2.96[95%置信区间:1.52 - 5.77])和朋友(ARRR = 5.78[95%置信区间:3.60 - 9.30]、4.98[95%置信区间:3.22 - 7.72]和6.61[95%置信区间:2.91 - 15.01])。HTP使用频率与戒烟尝试无关,除了每月使用HTP可预测持续≥30天的SQA(ARRR = 2.12[95%置信区间:1.17 - 3.85])。开始使用HTP与吸烟频率的变化无关。将分析局限于那些打算戒烟的人也得到了阴性结果。
在墨西哥成年吸烟者中,HTP的使用频率大多与戒烟行为或卷烟消费变化无关,这表明HTP在戒烟方面的有效性有限或几乎没有效果。