Guo Liyun, Dong Yumei, Qi Yuexiao, Tao Na, Song Haixia, Shao Lihua, Cai Yaqin, Xu Lijun, Wei Shihong
Altern Ther Health Med. 2024 May 24.
To investigate the risk factors for lung infection in lung cancer patients undergoing radiotherapy.
We selected 142 patients with lung cancer who underwent radiotherapy at our hospital from January 2020 to June 2021. The patients were divided into groups according to whether they had pulmonary infection during radiotherapy in our hospital, which was infected group (n=44) and the uninfected group (n=98), respectively. To observe the incidence of lung infection in lung cancer patients during radiotherapy. The distribution of pathogenic bacteria in patients with pulmonary infection was observed. Clinical data of the two groups were collected and compared. The risk factors of lung cancer patients complicated with lung infection were analyzed by binary Logistic regression.
All patients with lung cancer complicated with lung infection underwent relevant examination, and the results showed that they were all complicated infections, and the composition ratio of Klebsiella pneumoniae was the highest (31.82%), followed by Staphylococcus, Pseudomonas, and fungi, which accounted for 27.27%, 22.73%, and 18.18%, respectively. Binary Logistic regression analysis showed that age ≥60 years old, smoking history ≥30 years, radiotherapy duration of combined drug regimen > 2 weeks, pathogenic bacteria combined infection, albumin content < 30 g/L were risk factors for lung cancer patients during radiotherapy.
Age ≥60 years old, smoking history ≥30 years old, radiotherapy duration of combined drug regimen > 2 weeks, pathogenic bacteria combined infection, albumin content < 30 g/L are the risk factors for lung cancer patients during radiotherapy. Clinical prevention and intervention should be based on the aforementioned independent risk factors to decrease the incidence of lung infections, thereby enhancing patient prognosis.
探讨肺癌放疗患者肺部感染的危险因素。
选取2020年1月至2021年6月在我院接受放疗的142例肺癌患者。根据患者在我院放疗期间是否发生肺部感染将其分为感染组（n = 44）和未感染组（n = 98）。观察肺癌患者放疗期间肺部感染的发生率。观察肺部感染患者病原菌的分布情况。收集并比较两组的临床资料。采用二元Logistic回归分析肺癌患者合并肺部感染的危险因素。
所有肺癌合并肺部感染患者均进行了相关检查，结果显示均为合并感染，其中肺炎克雷伯菌构成比最高（31.82%），其次为葡萄球菌、假单胞菌和真菌，分别占27.27%、22.73%和18.18%。二元Logistic回归分析显示，年龄≥60岁、吸烟史≥30年、联合用药方案放疗时间>2周、病原菌合并感染、白蛋白含量<30 g/L是肺癌患者放疗期间的危险因素。
年龄≥60岁、吸烟史≥30岁、联合用药方案放疗时间>2周、病原菌合并感染、白蛋白含量<30 g/L是肺癌患者放疗期间的危险因素。临床预防和干预应基于上述独立危险因素，以降低肺部感染的发生率，从而改善患者预后。
