Harkiss G D
J Clin Pathol. 1985 Feb;38(2):193-7. doi: 10.1136/jcp.38.2.193.
C reactive protein (CRP) concentrations were measured serially in 38 patients after cardiac transplantation. Three of 28 patients (11%) had raised values before transplantation. After transplantation, most patients showed rises in CRP concentrations associated with transplant surgery which became normal by day 7. Thereafter, 75/274 samples (28%) from 18/38 patients (47%) had raised CRP values. Most of the rises in CRP concentration were associated with infection (78%), which in most cases was bacterial. No correlation was found between CRP values and acute cardiac rejection assessed histologically on serial endomyocardial biopsy.
对38例心脏移植患者术后的C反应蛋白(CRP)浓度进行了连续监测。28例患者中有3例(11%)在移植前CRP值升高。移植后,大多数患者的CRP浓度因移植手术而升高,并在第7天恢复正常。此后,38例患者中有18例(47%)的274份样本中有75份(28%)CRP值升高。CRP浓度的升高大多与感染有关(78%),在大多数情况下为细菌感染。在连续心内膜心肌活检中,CRP值与经组织学评估的急性心脏排斥反应之间未发现相关性。