噬菌体修饰因子对其靶分子产量增加的反应。
Response of a phage modification factor to enhanced production of its target molecule.
作者信息
Olson N J, Marchin G L
出版信息
J Virol. 1985 Feb;53(2):702-4. doi: 10.1128/JVI.53.2.702-704.1985.
Abstract
Escherichia coli cells with plasmids bearing the valS gene were constructed from the Clark-Carbon collection. Their increased valyl-tRNA synthetase (EC 6.1.1.9) activity was not matched by commensurate production of a modifying peptide during T4 infection. Thus, phage vs gene expression is set to modify the normal amount of valyl-tRNA synthetase activity.
摘要
携带valS基因的质粒的大肠杆菌细胞是从克拉克-卡本收集物构建而来的。在T4感染期间，它们增加的缬氨酰-tRNA合成酶（EC 6.1.1.9）活性与修饰肽的相应产量不匹配。因此，噬菌体vs基因表达被设定为改变缬氨酰-tRNA合成酶活性的正常量。
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