Ankara Training and Research Center, Department of Dermatology and Venerology, Health Sciences University, Ankara, Turkey.
J Cosmet Dermatol. 2024 Oct;23(10):3382-3387. doi: 10.1111/jocd.16417. Epub 2024 May 30.
The changes in the skin caused by obesity may predispose patients with rosacea to Demodex infestation (DI). Besides, identifying predisposing factors in these patients is important for initial treatment plan.
The main purpose of this study is to determine the relationship between DI and obesity in patients with rosacea.
Sociodemographic characteristics, body mass index, and clinical features of 130 rosacea patients were recorded. Demodex density was measured by noninvasive standard skin biopsy, and a determination of ≥5/cm mites was regarded as positive for DI. Patients with a BMI of 30 and above were categorized as the obese group, and those with a BMI below 30 were classified as the nonobese group. Moreover, patients were divided according to DI into positive and negative. These groups were compared with each other.
Upon comparing the patients with and without obesity, it was noted that the obese patients had significantly higher rates of erythematotelangiectatic type rosacea, rosacea severity, and flushing complaints. Furthermore, results show that the DI was significantly more common in obese patients. The most determinant factors for predicting DI in rosacea patients were papulopustular type rosacea, obesity, and rosacea severity, respectively.
In this study, DI was found to be more common in obese patients with rosacea. Besides, obesity was found to be one of the most determining factors in detecting DI in patients with rosacea.
肥胖引起的皮肤变化可能使酒渣鼻患者易患螨虫感染（DI）。此外，确定这些患者的易患因素对于初始治疗计划很重要。
本研究的主要目的是确定 DI 与酒渣鼻患者肥胖之间的关系。
记录了 130 例酒渣鼻患者的社会人口统计学特征、体重指数和临床特征。通过非侵入性标准皮肤活检测量螨虫密度，≥5/cm 螨虫被认为 DI 阳性。BMI 为 30 及以上的患者被归类为肥胖组，BMI 低于 30 的患者被归类为非肥胖组。此外，根据 DI 将患者分为阳性和阴性。将这些组相互比较。
在比较肥胖和非肥胖患者时，发现肥胖患者的红斑毛细血管扩张型酒渣鼻、酒渣鼻严重程度和潮红抱怨的发生率明显更高。此外，结果表明肥胖患者的 DI 更为常见。预测酒渣鼻患者 DI 的最决定因素分别是丘疹脓疱型酒渣鼻、肥胖和酒渣鼻严重程度。
在这项研究中，发现肥胖的酒渣鼻患者中 DI 更为常见。此外，肥胖被发现是检测酒渣鼻患者 DI 的最决定因素之一。
