摩加迪沙一家转诊医院儿童的抗菌药物耐药模式及尿路病原体分布
Antimicrobial resistance pattern and uropathogens distribution in children visiting a referral hospital in Mogadishu.
作者信息
Mohamed Abdikarin Ahmed, Bastug Yavuz, Senol Cem, Kassim Mohamed Muktar, Yusuf Abdisalam Abdullahi, Mohamed Abdikarim Hussein
机构信息
Department of Pediatrics & Child Health, Mogadishu Somalia Turkish Training & Research Hospital, Mogadishu, Somalia.
University of Somalia, Mogadishu, Somalia.
出版信息
Future Sci OA. 2024 May 15;10(1):FSO978. doi: 10.2144/fsoa-2023-0298. eCollection 2024.
Studies concerning epidemiology and drug susceptibility patterns of pediatric urinary tract infection in developing countries are scarce. This study aimed to evaluate the antimicrobial resistance pattern and uropathogens distribution in children. Four-year retrospective study included 840 participants in all pediatric age groups whose urine had been cultured. The prevalence of culture-proven pediatric UTIs was 17.6% (148/840). was the most common pathogen isolated from the cultures, accounting for (48%, 71/148), followed by (16.2%, 24/148). About 27% of the pathogens had a multidrug-resistant (MDR) pattern. A resistance rate against nitrofurantoin at 24.6%, fosfomycin at 15.2% and trimethoprim-sulfamethoxazole (SMX-TMP) at 79.7% was noted. and were the most common pathogens isolated.
关于发展中国家儿童尿路感染的流行病学和药敏模式的研究很少。本研究旨在评估儿童的抗菌药物耐药模式和尿路病原体分布。一项为期四年的回顾性研究纳入了所有儿科年龄组中840名尿液已进行培养的参与者。经培养证实的儿童尿路感染患病率为17.6%（148/840）。是从培养物中分离出的最常见病原体，占（48%，71/148），其次是（16.2%，24/148）。约27%的病原体具有多重耐药（MDR）模式。观察到对呋喃妥因的耐药率为24.6%，对磷霉素的耐药率为15.2%，对甲氧苄啶-磺胺甲恶唑（SMX-TMP）的耐药率为79.7%。和是分离出的最常见病原体。
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