姜黄提取物凝胶联合蜂蜜在剖宫产术后切口愈合中的应用：初步研究。
Turmeric extract gel and honey in post-cesarean section wound healing: A preliminary study.
机构信息
Midwifery, graduate school, Universitas Hasanuddin, Makassar, South Sulawesi, 90245, Indonesia.
Faculty of Pharmacy, Hasanuddin University, Indonesia, Universitas Hasanuddin, Makassar, South Sulawesi, 90245, Indonesia.
出版信息
F1000Res. 2024 Feb 20;12:1095. doi: 10.12688/f1000research.134011.2. eCollection 2023.
BACKGROUND
Delivery by cesarean section (SC) increases the risk of a surgical site infection (SSI). Therapy from health services and complementary therapy reduce the risk of infection and accelerate the wound-healing process. This study compared wound healing after SC with a turmeric extract gel and original Trigona honey.
METHODS
Female white rats ( ) with pre- and post-testing and a control group were included in this experiment, which was conducted in June-July 2022. The test animals were 56 female white rats, 2-4 months old, weighing 150-350 g. The treatment group was divided into three subgroups with application of 50% and 75% turmeric extract gel and Trigona honey. The turmeric was given twice daily, and the honey was divided into two applications of twice a day and once a day. Wounds were assessed using the Reeda Scale.
RESULTS
The fastest wound healing occurred in the group given Trigona honey twice daily. Redness, ecchymosis, and edema disappeared in this group on day 9 (score 0), and granulation tissue formed on day 9. The group that was administered 50% and 75% turmeric gel extract and Trigona honey once a day healed by days 12 and 15, respectively; all three of these interventions were better than the control group.
CONCLUSIONS
Administering Trigona honey twice daily was more effective for accelerating wound healing than the 50% or 75% turmeric extract gel. Original Trigona honey has the potential to be a post-SC wound healing agent.
背景
剖宫产（CS）会增加手术部位感染（SSI）的风险。来自医疗保健服务和补充疗法的治疗可以降低感染风险并加速伤口愈合过程。本研究比较了 CS 术后使用姜黄提取物凝胶和原始 Trigona 蜂蜜的伤口愈合情况。
方法
本实验纳入了雌性白色大鼠（），进行了预测试和后测试以及对照组，实验于 2022 年 6 月至 7 月进行。试验动物为 56 只 2-4 月龄、体重 150-350g 的雌性白色大鼠。治疗组分为应用 50%和 75%姜黄提取物凝胶和 Trigona 蜂蜜的三个亚组。姜黄每天应用两次，蜂蜜每天应用两次和一次。使用 Reeda 量表评估伤口。
结果
每日两次给予 Trigona 蜂蜜的组伤口愈合最快。该组第 9 天（评分为 0）时红肿、瘀伤和水肿消失，第 9 天形成肉芽组织。给予 50%和 75%姜黄凝胶提取物和 Trigona 蜂蜜每日一次的组分别在第 12 天和第 15 天愈合；所有这三种干预措施均优于对照组。
结论
每日两次给予 Trigona 蜂蜜加速伤口愈合的效果优于 50%或 75%姜黄提取物凝胶。原始 Trigona 蜂蜜有潜力成为 CS 术后伤口愈合剂。
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