Kariyawasam Vidhu, Shah Kairav
Infectious Diseases, University of Florida, Gainesville, USA.
Infectious Diseases, Southern Regional Medical Center, Atlanta, USA.
Cureus. 2024 Apr 30;16(4):e59369. doi: 10.7759/cureus.59369. eCollection 2024 Apr.
Ehrlichiosis is a tick-borne illness that has been recognized as a source of human infection with increased incidence in the United States over the last decade. The usual presentation is with acute febrile illness, myalgia, malaise with confusion, and central nervous system abnormalities, along with laboratory data concerning transaminitis and hematological abnormalities. Though many complications have been associated with Ehrlichiosis, very few cardiac complications have been reported. We report a rare presentation of Ehrlichiosis in a 63-year-old female who presented with acute fever, transaminitis, and renal failure followed by the development of myocarditis. As part of the diagnostic work-up, an examination of the peripheral smear revealed intracytoplasmic granules in monocytes, which were later confirmed through serology to have Ehrlichia chaffeensis (E. chaffeensis). Given the high degree of initial clinical suspicion, the patient was started on empiric doxycycline and fully recovered with no disease-associated sequelae.
埃立克体病是一种由蜱传播的疾病,在过去十年中,在美国已被确认为人类感染的一个来源,其发病率呈上升趋势。常见症状为急性发热性疾病、肌痛、伴有意识模糊的不适以及中枢神经系统异常,同时伴有转氨酶升高和血液学异常的实验室检查数据。虽然埃立克体病与许多并发症有关,但报道的心脏并发症却很少。我们报告了一例63岁女性埃立克体病的罕见病例,该患者表现为急性发热、转氨酶升高和肾衰竭,随后发展为心肌炎。作为诊断检查的一部分,对外周血涂片的检查发现单核细胞内有细胞质颗粒,后来通过血清学证实感染了查菲埃立克体(E. chaffeensis)。鉴于最初高度的临床怀疑,患者开始接受经验性强力霉素治疗,最终完全康复,没有出现与疾病相关的后遗症。