Alharbi Mohannad, Alshamsan Bader, Almansour Mohammed, Alharbi Abdullah, Algaadi Adel, Abdelhafez Mohamed F
Department of Surgery, College of Medicine, Qassim University, Buraidah, Qassim, Saudi Arabia.
Department of Urology, King Fahad Specialist Hospital, Buraidah, Qassim, Saudi Arabia.
Urol Ann. 2024 Apr-Jun;16(2):150-154. doi: 10.4103/ua.ua_74_23. Epub 2024 Apr 18.
Holmium laser enucleation of the prostate (HoLEP) showed higher efficacy than transurethral resection for treating benign prostatic hyperplasia (BPH). The present study aims to report the outcome of BPH treatment by HoLEP in a tertiary center.
An observational prospectively collected data for consecutive symptomatic BPH patients undergoing HoLEP between January 2020 and December 2021. Demographic and perioperative data were collected with the International Prostate Symptom Score (IPSS), quality of life, peak flow rate (Q), residual urine postvoid residual (PVR), and prostate-specific antigen (PSA) changes, in addition to perioperative and late adverse events.
One hundred patients were included with a median age of 73 years (range 65-80). The IPSS improved by 80% postoperatively (25 vs. 5, < 0.001). Similarly, Q significantly improved. Seven patients were found to have incidental prostate cancer. No patient needed a perioperative blood transfusion. Compared to its preoperative values, follow-up PSA has been reduced by 75% ( < 0.001). Urethral stricture and bladder neck contracture were noted in < 2% of the patients.
HoLEP is feasible for all prostate sizes and a safe and effective treatment for BPH patients; our results are consistent with the reported data in the literature regarding functional outcomes, complication rates, and urinary incontinence rates.
钬激光前列腺剜除术(HoLEP)在治疗良性前列腺增生(BPH)方面显示出比经尿道前列腺切除术更高的疗效。本研究旨在报告三级中心采用HoLEP治疗BPH的结果。
对2020年1月至2021年12月期间连续接受HoLEP治疗的有症状BPH患者进行前瞻性观察性数据收集。除围手术期和晚期不良事件外,还收集了人口统计学和围手术期数据,包括国际前列腺症状评分(IPSS)、生活质量、峰值尿流率(Q)、排尿后残余尿量(PVR)以及前列腺特异性抗原(PSA)变化。
纳入100例患者,中位年龄73岁(范围65 - 80岁)。术后IPSS改善了80%(25分对5分,<0.001)。同样,Q也显著改善。发现7例患者伴有偶发前列腺癌。无患者需要围手术期输血。与术前值相比,随访时PSA降低了75%(<0.001)。<2%的患者出现尿道狭窄和膀胱颈挛缩。
HoLEP对所有前列腺大小均可行,是治疗BPH患者的一种安全有效的方法;我们的结果与文献中报道的关于功能结局、并发症发生率和尿失禁发生率的数据一致。