Herr H W, Pinsky C M, Whitmore W F, Sogani P G, Oettgen H F, Melamed M R
Urology. 1985 Feb;25(2):119-23. doi: 10.1016/0090-4295(85)90525-4.
Between March, 1978, and July, 1981, 86 patients with polychronotopic superficial papillary bladder tumors and concurrent carcinoma in situ were randomized to receive either transurethral resection alone (43) or TUR plus BCG (43). The results indicate that BCG is not only active in preventing recurrences of new tumors but also effective for the diffuse, flat carcinoma in situ.
在1978年3月至1981年7月期间，86例患有多灶性浅表乳头状膀胱肿瘤并伴有原位癌的患者被随机分为两组，一组仅接受经尿道切除术（43例），另一组接受经尿道切除术加卡介苗治疗（43例）。结果表明，卡介苗不仅对预防新肿瘤的复发有效，而且对弥漫性扁平原位癌也有疗效。
