Department of Orthopaedic Surgery, Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA.
Spine (Phila Pa 1976). 2024 Oct 1;49(19):1352-1360. doi: 10.1097/BRS.0000000000005057. Epub 2024 Jun 3.
Retrospective cohort study.
To determine whether the L1 pelvic angle (L1PA) can be used to predict quality of life outcomes for adults one year after L4-L5 fusion to treat degenerative spondylolisthesis.
L1PA is beneficial in the evaluation of preoperative and postoperative quality of life outcomes in patients undergoing surgery for spinal deformity. No studies have examined its utility in surgical patients with degenerative spinal disease.
Patients undergoing L4-L5 posterolateral decompression and fusion or transforaminal lumbar interbody fusion for degenerative lumbar spondylolisthesis were grouped by preoperative and postoperative L1PA, and further stratified by cut offs of >7.2° and <7.2° based on previous literature. We also stratified patients by presence of an ideal calculated L1PA, defined as (0.5×Pelvic incidence) -21 +/-5°, as proposed by prior literature. Preoperative, one-year postoperative and Δ (postoperative minus preoperative) patient-reported outcome measures (PROMs) and radiographic measurements were collected.
Twenty-four patients were identified with preoperative L1PAs <7.2° and 132 with L1PAs >7.2°. Eighteen patients were identified with postoperative L1PAs <7.2° and 138 with L1PAs>7.2°. Sixty-five and fifty-seven patients were identified as having ideal calculated preoperative and postoperative L1PAs, respectively. When using absolute cutoffs, L1PA correlated with pelvic tilt, pelvic incidence, and pelvic incidence-lumbar lordosis mismatch (PI-LL). When using calculated L1PAs, L1PA correlated with lumbar lordosis, PI-LL, pelvic tilt and sacral slope. With respect to PROMs, no statistically significant differences existed between cohorts both preoperatively and at one-year postoperatively on either univariate and multivariate analyses.
L1PA may be a helpful radiographic consideration that translates to clinically relevant outcomes in spinal deformity. However, it does not appear as predictive of patient outcomes after single-level fusion for patients with L4-L5 degenerative spondylolisthesis. Further studies are warranted to investigate the role of L1PA in degenerative spine patients.
回顾性队列研究。
确定 L1 骨盆角(L1PA)是否可用于预测成人 L4-L5 融合治疗退行性脊椎滑脱症一年后的生活质量结果。
L1PA 有益于评估接受脊柱畸形手术的患者的术前和术后生活质量结果。尚无研究检查其在退行性脊柱疾病手术患者中的应用。
将接受 L4-L5 后路减压和融合或经椎间孔腰椎体间融合术治疗退行性腰椎滑脱症的患者根据术前和术后的 L1PA 分组,并根据先前文献中的>7.2°和<7.2°的截止值进一步分层。我们还根据先前文献中提出的理想计算的 L1PA(定义为(0.5×骨盆入射角)-21 +/-5°)的存在对患者进行分层。收集术前、术后一年和(术后减去术前)患者报告的结果测量(PROM)和影像学测量值。
确定了 24 例术前 L1PA<7.2°和 132 例 L1PA>7.2°的患者。确定了 18 例术后 L1PA<7.2°和 138 例 L1PA>7.2°的患者。分别确定了 65 例和 57 例具有理想术前和术后计算的 L1PA 的患者。使用绝对截止值时,L1PA 与骨盆倾斜度、骨盆入射角和骨盆入射角-腰椎前凸不匹配(PI-LL)相关。使用计算的 L1PA 时,L1PA 与腰椎前凸度、PI-LL、骨盆倾斜度和骶骨斜率相关。关于 PROM,在单变量和多变量分析中,两组患者术前和术后一年均无统计学差异。
L1PA 可能是一种有用的放射学考虑因素,可转化为脊柱畸形患者的临床相关结果。然而,它似乎不能预测 L4-L5 退行性脊椎滑脱症患者单节段融合后的患者结果。需要进一步研究来探讨 L1PA 在退行性脊柱患者中的作用。