Fall Arona, Magdei Mihaela, Savchuk Mariia, Oudeyer Sylvain, Beucher Hélène, Brière Jean-François
INSA Rouen Normandie, Univ Rouen Normandie, CNRS, Normandie Univ, COBRA UMR 6014, INC3M FR 3038, F-76000 Rouen, France.
Chem Commun (Camb). 2024 Jun 13;60(49):6316-6319. doi: 10.1039/d4cc01766h.
Herein, we disclose an eco-efficient redox-neutral iron-catalyzed decarboxylative radical addition to chiral azomethine imines upon visible light (427 nm) giving cyclic hydrazine derivatives with dr ranging from 82 : 18 to >96 : 4. This earth-abundant metal promoted sequence proceeds efficiently under ligand-free conditions based on a LMCT process and opens a route to new chiral heterocycles.
在此，我们公开了一种环境友好的氧化还原中性铁催化的可见光（427 nm）作用下的手性甲亚胺叶立德的脱羧自由基加成反应，生成非对映体比例（dr）范围为82:18至>96:4的环状肼衍生物。这种以地球上储量丰富的金属促进的反应序列基于光激发电子转移过程在无配体条件下高效进行，并为新型手性杂环开辟了一条途径。
