Sunderman F W
Ann Clin Lab Sci. 1985 Jan-Feb;15(1):1-12.
An historical review of clinical hemoglobinometry has been presented. Investigators who have made important contributions to our knowledge of hemoglobin have been cited. A questionnaire was distributed to 750 clinical laboratories in the United States to ascertain (a) the type of instrumentation used routinely to measure hemoglobin; (b) the methods that are now being used for clinical hemoglobinometry; (c) reference material that is used for daily quality control; and (d) the methods used for primary standardization. The results of the 263 responses to the questionnaire are reported. It is noteworthy that at the present time, 78 percent of the responding laboratories use the same instrumentation system. An assessment has been made of the precision of hemoglobin measurements undertaken in clinical laboratories in the United States over the past four decades. The data indicate that hemoglobin measurements during the past four years have become significantly more precise. There is probably no single factor responsible for this timely improvement; however, it may be inferred that the shift from manual to automated methodology in recent years is an important contributing factor.
本文对临床血红蛋白测定法进行了历史回顾。文中引用了那些对我们了解血红蛋白做出重要贡献的研究人员。向美国750家临床实验室发放了一份调查问卷，以确定：(a) 日常用于测量血红蛋白的仪器类型；(b) 目前临床血红蛋白测定所采用的方法；(c) 用于日常质量控制的参考物质；以及(d) 用于一级标准化的方法。报告了对该问卷263份回复的结果。值得注意的是，目前，78% 的回复实验室使用相同的仪器系统。对美国临床实验室在过去四十年中进行的血红蛋白测量的精密度进行了评估。数据表明，过去四年中的血红蛋白测量变得明显更加精确。促成这一适时改进的可能并非单一因素；然而，可以推断，近年来从手工方法向自动化方法的转变是一个重要的促成因素。
