Azide-induced mutagenesis in gram-negative bacteria is recA-and lexA-independent.
作者信息
Szwacka M, Cieśla Z, Kłopotowski T
出版信息
Mutat Res. 1979 Sep;62(2):221-5. doi: 10.1016/0027-5107(79)90080-0.
PMID:388210
Abstract
Azide-induced mutagenesis was investigated in Salmonella typhimurium and Escherichia coli. Azide was highly effective in inducing mutation in uvrB, uvrB recA and uvrB recB mutants of S. typhimurium. The mutagenic effect of azide was also observed in uvrA lexA mutants of E. coli K12 and E. coli B/r. These results suggest that azide-induced mutagenesis is due to mis-replication of DNA.
摘要
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