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肺叶切除术后迟发性支气管胸膜瘘的表现和处理:一例报告。

Presentation and management of delayed bronchopleural fistula after pulmonary lobectomy: a case report.

机构信息

Department of General Surgery, King Hussein Cancer Center, Amman, Jordan.

Department of Surgery, King Hussein Cancer Centre, Amman, Jordan.

出版信息

J Cardiothorac Surg. 2024 May 31;19(1):311. doi: 10.1186/s13019-024-02795-8.

Abstract

BACKGROUND

Lung cancer is the second most diagnosed cancer and the leading cause of cancer deaths worldwide. Surgical lung resection is the best treatment modality in the early stages of lung cancer as well as in some locally advanced cases. Postoperative air leak is one of the most common complications after pulmonary resection with incidence ranging between 20 and 33%. The majority of air leaks seal, within 5 days after surgery, on their own by conservative management. However, at least 5% of patients still have prolonged air coming out from the residual lung at discharge. This report describes the management of a thin lady with right lung cancer who underwent a right lower lobectomy and then suffered from a delayed air leak 7 weeks after surgery and required extensive thoracic and general surgery collaboration.

CASE PRESENTATION

A 72-year-old heavy smoker female patient diagnosed with stage I lung cancer underwent right robotic-assisted thoracoscopic surgery converted to thoracotomy because of a fused fissure, right lower lobectomy, and mediastinal lymphadenectomy presented with delayed air leak 49 days after surgery. VATS decortication and mechanical pleurodesis were done 2 weeks after unsuccessful conservative treatment. Still, the lung failed to expand four weeks later so the patient was sent to surgery; she is underweight (BMI of 18) with not many options for a big flap to fill the chest cavity empty space. Accordingly; the decision was to use multiple pedicle flaps; omentum, intercostal muscle, and serratus anterior muscle to cover the bronchopleural fistulas and fill the pleural space in addition to mechanical and chemical pleurodesis. Full expansion of the lung was obtained. The patient was discharged on Post-Operative day 5 without remnant pneumothorax.

CONCLUSIONS

Air leaks After lobectomy usually presents directly postoperatively; various management options are available ranging from conservative and minimally invasive to major operative treatment. We presented what we believe was unusual delayed bronchopleural fistula post-lobectomy in a thin lady which demonstrates clearly how a delayed air leak was detected and how collaborative efforts were crucial for delivering high-quality, safe, and patient-centered care till treated and complete recovery.

摘要

背景

肺癌是全球第二大被诊断出的癌症,也是癌症死亡的主要原因。手术切除肺是治疗肺癌早期以及某些局部晚期病例的最佳方法。术后肺漏气是肺切除术后最常见的并发症之一,发生率在 20%至 33%之间。大多数漏气会自行愈合,无需特殊处理。然而,至少有 5%的患者在出院时仍有持续性的肺部漏气。本报告描述了一位瘦弱的女性肺癌患者的治疗过程,她接受了右下肺叶切除术,术后 7 周出现延迟性肺漏气,需要胸外科和普通外科的广泛协作。

病例介绍

一位 72 岁的重度吸烟者女性患者被诊断为 I 期肺癌,接受了机器人辅助右胸腹腔镜手术,因融合裂孔改行开胸手术,行右下肺叶切除术和纵隔淋巴结清扫术,术后 49 天出现延迟性肺漏气。在保守治疗失败后 2 周进行了胸腔镜下剥脱术和机械性胸膜固定术。然而,4 周后肺部仍未扩张,因此患者被转至外科手术;她体重过轻(BMI 为 18),没有太多的大瓣来填补胸腔的空洞。因此,决定使用多个带蒂瓣,包括大网膜、肋间肌和前锯肌,覆盖支气管胸膜瘘,并填充胸膜腔,同时进行机械和化学性胸膜固定术。最终肺部完全扩张。患者在术后第 5 天无残余气胸出院。

结论

肺叶切除术后的漏气通常直接发生在术后,有多种治疗方法可供选择,包括保守治疗、微创手术和大手术治疗。我们报告了一例瘦弱女性罕见的延迟性支气管胸膜瘘,该患者明确显示了如何检测到延迟性肺漏气,以及如何通过协作努力为患者提供高质量、安全和以患者为中心的治疗,直至治愈和完全康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1026/11140999/9acb71d43d2b/13019_2024_2795_Fig2_HTML.jpg

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