利用电子健康记录数据检查髋部骨折后急性护理期间的按需镇痛剂给药。

Use of electronic health record data to examine administrations of pro re nata analgesics during hip fracture post-acute care.

机构信息

Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA.

Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA.

出版信息

Pharmacoepidemiol Drug Saf. 2024 Jun;33(6):e5846. doi: 10.1002/pds.5846.

Abstract

PURPOSE

Medications prescribed to older adults in US skilled nursing facilities (SNF) and administrations of pro re nata (PRN) "as needed" medications are unobservable in Medicare insurance claims. There is an ongoing deficit in our understanding of medication use during post-acute care. Using SNF electronic health record (EHR) datasets, including medication orders and barcode medication administration records, we described patterns of PRN analgesic prescribing and administrations among SNF residents with hip fracture.

METHODS

Eligible participants resided in SNFs owned by 11 chains, had a diagnosis of hip fracture between January 1, 2018 to August 2, 2021, and received at least one administration of an analgesic medication in the 100 days after the hip fracture. We described the scheduling of analgesics, the proportion of available PRN doses administered, and the proportion of days with at least one PRN analgesic administration.

RESULTS

Among 24 038 residents, 57.3% had orders for PRN acetaminophen, 67.4% PRN opioids, 4.2% PRN non-steroidal anti-inflammatory drugs, and 18.6% PRN combination products. The median proportion of available PRN doses administered per drug was 3%-50% and the median proportion of days where one or more doses of an ordered PRN analgesic was administered was 25%-75%. Results differed by analgesic class and the number of administrations ordered per day.

CONCLUSIONS

EHRs can be leveraged to ascertain precise analgesic exposures during SNF stays. Future pharmacoepidemiology studies should consider linking SNF EHRs to insurance claims to construct a longitudinal history of medication use and healthcare utilization prior to and during episodes of SNF care.

摘要

目的

在美国熟练护理机构(SNF)中为老年人开的处方药物和按需开具的“临时”(PRN)药物在医疗保险索赔中是不可观察的。我们对急性后期护理期间的药物使用情况的了解一直存在不足。本研究利用 SNF 电子健康记录(EHR)数据集,包括药物医嘱和条形码药物管理记录,描述了伴有髋部骨折的 SNF 居民 PRN 镇痛药物的开具和使用模式。

方法

合格的参与者居住在由 11 个连锁机构所有的 SNF 中,在 2018 年 1 月 1 日至 2021 年 8 月 2 日期间被诊断为髋部骨折,并且在髋部骨折后 100 天内至少接受了一次镇痛药物的治疗。我们描述了镇痛药物的安排、可用 PRN 剂量的给药比例以及至少有一次 PRN 镇痛药物给药的天数比例。

结果

在 24038 名居民中,57.3%有 PRN 对乙酰氨基酚的医嘱,67.4%有 PRN 阿片类药物的医嘱,4.2%有 PRN 非甾体抗炎药的医嘱,18.6%有 PRN 联合产品的医嘱。每种药物的可用 PRN 剂量给药比例中位数为 3%-50%,每天有一个或多个规定的 PRN 镇痛药物剂量给药的天数中位数为 25%-75%。结果因镇痛药物类别和每天规定的给药次数而异。

结论

EHR 可用于确定 SNF 入住期间的精确镇痛药物暴露情况。未来的药物流行病学研究应考虑将 SNF EHR 与保险索赔相联系,以构建 SNF 护理之前和期间药物使用和医疗保健利用的纵向历史。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索