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眶周坏死性筋膜炎:从发病到重建

Periorbital Necrotizing Fasciitis: Presentation to Reconstruction.

作者信息

Arun Kirupakaran, Shah Prachi, Grillon Fiorella, Subak-Sharpe Ian

机构信息

Ophthalmology, Moorfields NHS Trust, London, GBR.

Ophthalmology, Whipps Cross Hospital, London, GBR.

出版信息

Cureus. 2024 May 2;16(5):e59501. doi: 10.7759/cureus.59501. eCollection 2024 May.

Abstract

Periorbital necrotizing fasciitis (NF) is a devastating bacterial infection associated with irreversible inflammatory destruction of soft tissues. Outcomes include disfigurement, vision loss, septic shock, and death within hours to days. We describe two cases of periorbital NF that presented to our unit within a three-month period. We aim to highlight the key clinical features of periorbital NF, demonstrate the rapid progression of the disease, and the need for prompt identification and decisive intervention. Both patients presented with fever and left-sided periorbital swelling and showed rapid progression of swelling and gangrenous changes to the periorbital skin with worsening proptosis. They were treated with broad-spectrum intravenous antibiotics and underwent emergency surgical debridement of necrotic tissue followed by reconstruction. We propose a formal protocol that we recommend to aid the diagnosis and management of periorbital NF in an acute setting.

摘要

眶周坏死性筋膜炎(NF)是一种毁灭性的细菌感染,伴有软组织不可逆的炎症性破坏。其后果包括毁容、视力丧失、感染性休克以及在数小时至数天内死亡。我们描述了在三个月内就诊于我们科室的两例眶周NF病例。我们旨在强调眶周NF的关键临床特征,展示该疾病的快速进展,以及及时识别和果断干预的必要性。两名患者均表现为发热和左侧眶周肿胀,并出现肿胀迅速进展以及眶周皮肤坏疽性改变,伴有眼球突出加重。他们接受了广谱静脉抗生素治疗,并接受了坏死组织的紧急手术清创,随后进行了重建手术。我们提出了一个正式的方案,建议在急性情况下辅助眶周NF的诊断和管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e08/11144053/57da784f2c7a/cureus-0016-00000059501-i01.jpg

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