Ssenyonjo Jude, Shrestha Roman, Copenhaver Michael
Department of Allied Health Sciences, University of Connecticut, Storrs, CT, USA.
Institute for Collaboration on Health, Intervention, and Policy, University of Connecticut, Storrs, CT, USA.
Int J HIV AIDS Prev Educ Behav Sci. 2019 Dec;5(2):134-140. doi: 10.11648/j.ijhpebs.20190502.18. Epub 2019 Nov 17.
Despite evidence from recent trials of the efficacy of pre-exposure prophylaxis (PrEP) in reducing the risk of contracting HIV, PrEP uptake has been slow due to a range of social, structural, and behavioral factors. In this systematic review, we examined the influence of stigma on the PrEP care continuum among men and transwomen who have sex with men (MTWSM). We conducted a literature search in the PubMed electronic database (2012-2018) that focused on the PrEP care continuum among high-risk MTWSM. We explored studies that specifically looked at the influence of stigma on the PrEP cascade among these socially disadvantaged populations. Our search yielded 161 articles, of which nine were ultimately included in our systematic review. The results showed a significant association between stigma and unwillingness to seek or use PrEP suggesting that stigma may negatively affect willingness and uptake of PrEP among these high-risk groups.
尽管近期试验证明暴露前预防(PrEP)在降低感染艾滋病毒风险方面具有疗效,但由于一系列社会、结构和行为因素,PrEP的采用率一直很低。在这项系统评价中,我们研究了耻辱感对男男性行为者(MTWSM)中PrEP护理连续过程的影响。我们在PubMed电子数据库(2012 - 2018年)中进行了文献检索,重点关注高危MTWSM中的PrEP护理连续过程。我们探讨了专门研究耻辱感对这些社会弱势群体中PrEP级联反应影响的研究。我们的检索产生了161篇文章,其中9篇最终被纳入我们的系统评价。结果显示耻辱感与不愿寻求或使用PrEP之间存在显著关联,这表明耻辱感可能会对这些高危群体中PrEP的意愿和采用率产生负面影响。