老年血液透析患者的衰弱状况及其与抑郁、功能状态、透析充分性的关系。
The frailty in older hemodialysis patients and associations with depression, functional status, dialysis adequacy.
机构信息
Internal Medicine Nursing Department, Istanbul, Turkey.
Dialysis Department, Istanbul Medipol University, Health Vocational School, Istanbul, Turkey.
出版信息
Ther Apher Dial. 2024 Oct;28(5):727-734. doi: 10.1111/1744-9987.14164. Epub 2024 Jun 3.
INTRODUCTION
The aim of this study was to determine the level of frailty in older hemodialysis patients and to examine the relationship between their functional capacity, depression, and laboratory variables.
METHOD
This was a cross-sectional study, and the data were collected 243 dialysis patients aged 65 and over between May 2021 and May 2022.
RESULTS
The frailty rate was 49%. A statistically significant positive correlation was found between the frailty and age, hemodialysis vintage, and the number of hospitalizations. The frailty was negatively correlated with body mass index, Kt/V, Albumin, and parathyroid hormone. There was a statistically significant positive correlation between frailty and depression and a negative correlation between functional capacity.
CONCLUSION
A relationship was found between frailty and depression, functional capacity, and laboratory variables. In addition, the variables affecting the level of frailty in geriatric dialysis patients included dialysis vintage, dialysis adequacy, number of hospitalizations, albumin level, and patient weight.
简介
本研究旨在确定老年血液透析患者的衰弱程度，并探讨其功能能力、抑郁和实验室变量之间的关系。
方法
这是一项横断面研究，数据采集于 2021 年 5 月至 2022 年 5 月期间 243 名年龄在 65 岁及以上的透析患者。
结果
衰弱发生率为 49%。衰弱与年龄、血液透析年限和住院次数呈正相关。衰弱与体重指数、Kt/V、白蛋白和甲状旁腺激素呈负相关。衰弱与抑郁呈显著正相关，与功能能力呈负相关。
结论
衰弱与抑郁、功能能力和实验室变量之间存在关系。此外，影响老年透析患者衰弱程度的变量包括透析年限、透析充分性、住院次数、白蛋白水平和患者体重。
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