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通过检查实验穆勒矩阵的物理可实现性对成像偏振数据进行高效时间滤波。

Time-efficient filtering of imaging polarimetric data by checking physical realizability of experimental mueller matrices.

作者信息

Novikova Tatiana, Ovchinnikov Alexey, Pogudin Gleb, Ramella-Roman Jessica C

机构信息

LPICM, CNRS, Ecole polytechnique, IP Paris, Route de Saclay, Palaiseau, 91120, France.

Department of Biomedical Engineering, Florida International University, West Flagler Street, Miami, FL 33174, USA.

出版信息

Bioinformatics. 2024 Jun 3;40(7). doi: 10.1093/bioinformatics/btae348.

DOI:10.1093/bioinformatics/btae348
PMID:38830086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11283285/
Abstract

MOTIVATION

Imaging Mueller polarimetry has already proved its potential for biomedicine, remote sensing and metrology. The real-time applications of this modality require both video rate image acquisition and fast data post-processing algorithms. First, one must check the physical realizability of the experimental Mueller matrices in order to filter out non-physical data, ie to test the positive semi-definiteness of the 4 × 4 Hermitian coherency matrix calculated from the elements of corresponding Mueller matrix pixel-wise. For this purpose, we compared the execution time for the calculations of i) eigenvalues, ii) Cholesky decomposition, iii) Sylvester's criterion, and iv) coefficients of the characteristic polynomial (two different approaches) of the Hermitian coherency matrix, all calculated for the experimental Mueller matrix images (600 pixels × 700 pixels) of mouse uterine cervix. The calculations were performed using C ++ and Julia programming languages.

RESULTS

Our results showed the superiority of the algorithm iv) based on the simplification via Pauli matrices over other algorithms for our dataset. The sequential implementation of latter algorithm on a single core already satisfies the requirements of real-time polarimetric imaging. This can be further amplified by the proposed parallelization (e.g., we achieve a 5-fold speed up on 6 cores).

AVAILABILITY AND IMPLEMENTATION

The source codes of the algorithms and experimental data are available at https://github.com/pogudingleb/mueller_matrices.

摘要

动机

成像穆勒偏振测量法已证明其在生物医学、遥感和计量学方面的潜力。这种方法的实时应用需要视频速率图像采集和快速数据后处理算法。首先,必须检查实验穆勒矩阵的物理可实现性,以便滤除非物理数据,即按像素测试从相应穆勒矩阵元素计算出的4×4厄米特相干矩阵的半正定性。为此,我们比较了对小鼠子宫颈的实验穆勒矩阵图像(600像素×700像素)计算厄米特相干矩阵的以下各项的执行时间:i)特征值,ii)乔列斯基分解,iii)西尔维斯特准则,以及iv)特征多项式的系数(两种不同方法)。计算使用C++和Julia编程语言进行。

结果

我们的结果表明,对于我们的数据集,基于泡利矩阵简化的算法iv)优于其他算法。后一种算法在单核上的顺序实现已经满足实时偏振成像的要求。通过所提出的并行化可以进一步提高速度(例如,我们在6核上实现了5倍的加速)。

可用性和实现

算法的源代码和实验数据可在https://github.com/pogudingleb/mueller_matrices获取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a0d/11283285/9e44780d6d1e/btae348f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a0d/11283285/04a9e40889af/btae348f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a0d/11283285/9e44780d6d1e/btae348f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a0d/11283285/04a9e40889af/btae348f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0a0d/11283285/9e44780d6d1e/btae348f2.jpg

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本文引用的文献

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Effect of matrix properties on transmission and reflectance mode division-of-focal-plane Stokes polarimetry.基质特性对透射和反射式焦平面分束斯太尔偏光测量的影响。
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Is a complete Mueller matrix necessary in biomedical imaging?生物医学成像中是否需要完整的 Mueller 矩阵?
Opt Lett. 2022 Nov 1;47(21):5549-5552. doi: 10.1364/OL.471239.
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Digital histology of tissue with Mueller microscopy and FastDBSCAN.使用穆勒显微镜和快速密度空间聚类算法(FastDBSCAN)对组织进行数字组织学分析。
Appl Opt. 2022 Nov 10;61(32):9616-9624. doi: 10.1364/AO.473095.
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Mueller matrix imaging for collagen scoring in mice model of pregnancy.用于妊娠小鼠模型胶原评分的 Mueller 矩阵成像。
Sci Rep. 2021 Aug 2;11(1):15621. doi: 10.1038/s41598-021-95020-8.
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Embossed topographic depolarisation maps of biological tissues with different morphological structures.具有不同形态结构的生物组织的浮雕地形去极化图。
Sci Rep. 2021 Feb 16;11(1):3871. doi: 10.1038/s41598-021-83017-2.
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Analysis of tissue microstructure with Mueller microscopy: logarithmic decomposition and Monte Carlo modeling.用 Mueller 显微镜分析组织微观结构:对数分解和蒙特卡罗建模。
J Biomed Opt. 2020 Jan;25(1):1-11. doi: 10.1117/1.JBO.25.1.015002.
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Mueller Matrix Measurement of Electrospun Fiber Scaffolds for Tissue Engineering.用于组织工程的电纺纤维支架的穆勒矩阵测量
Polymers (Basel). 2019 Dec 11;11(12):2062. doi: 10.3390/polym11122062.
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Differential Mueller matrix imaging of partially depolarizing optically anisotropic biological tissues.部分去偏光各向异性生物组织的差动 Mueller 矩阵成像。
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In vivo imaging of uterine cervix with a Mueller polarimetric colposcope.用穆勒偏光阴道镜对子宫颈进行体内成像。
Sci Rep. 2017 Jun 1;7(1):2471. doi: 10.1038/s41598-017-02645-9.
10
Mueller polarimetric imaging for surgical and diagnostic applications: a review.用于手术和诊断应用的穆勒偏振成像:综述
J Biophotonics. 2017 Aug;10(8):950-982. doi: 10.1002/jbio.201600152. Epub 2017 May 2.