Rahman Md Mahfuzur, Morshed Md Niaz, Adnan Saleh Mohammad, Howlader Mohammad Tofazzal Hossain
Insect Biotechnology and Biopesticide Laboratory, Department of Entomology, Bangladesh Agricultural University, Bangladesh.
Lecturer, Department of Entomology, EXIM Bank Agricultural University Bangladesh, Nawabganj-6300, Bangladesh.
Heliyon. 2024 May 17;10(11):e31453. doi: 10.1016/j.heliyon.2024.e31453. eCollection 2024 Jun 15.
Mosquitoes are known vectors that transmit deadly diseases to millions of people across the globe. The reliance on synthetic insecticides has been the sole way to combat mosquito vectors for decades. In recent years, the extensive use of conventional insecticides in mosquito suppression has led to significant pesticide resistance and serious human health hazards. In this light, investigating the potential application of biorational compounds for vector management has drawn significant attention. We, hereby, evaluated the efficacy of three microbial derivative biorational insecticides, abamectin, spinosad, and buprofezin, and two botanical oils, neem ( A. Juss) and karanja oil ( Linn.) against the under laboratory conditions. The fourth-instar larvae were exposed to different concentrations of the selected larvicides and lethality was estimated based on LC and LT with Probit analysis. All larvicides showed concentration-dependent significant effects on survival and demonstrated larvicidal activity against larvae. However, abamectin exerted the highest toxicity (LC = 10.36 ppm), exhibited statistically significant effects on larval mortality, followed by spinosad (LC = 21.32 ppm) and buprofezin (LC = 56.34 ppm). Abamectin caused larval mortality ranged from 30.00 to 53.33 % and 53.00-70.00 % at 06 and 07 h after treatment (HAT), respectively. In the case of botanicals, karanja oil (LC = 216.61 ppm) was more lethal (more than 1.5 times) and had a shorter lethal time than neem oil (LC = 330.93 ppm) and showed a classic pattern of relationship between concentrations and mortality over time. Overall, the present study highlighted the potential of deploying new generation biorational pesticides and botanicals in mosquito vector control programs.
蚊子是已知的病媒，可将致命疾病传播给全球数百万人。几十年来，依赖合成杀虫剂一直是对抗蚊子病媒的唯一方法。近年来，在抑制蚊子方面广泛使用传统杀虫剂已导致显著的抗药性和严重的人类健康危害。有鉴于此，研究生物合理化合物在病媒管理中的潜在应用已引起广泛关注。在此，我们评估了三种微生物衍生的生物合理杀虫剂阿维菌素、多杀霉素和噻嗪酮，以及两种植物油印楝（印楝属）油和麻疯树油在实验室条件下对（某种蚊子）的效果。将四龄幼虫暴露于不同浓度的选定杀幼虫剂中，并通过概率分析基于致死浓度（LC）和致死时间（LT）估计死亡率。所有杀幼虫剂对存活率均显示出浓度依赖性显著影响，并对（该种）幼虫表现出杀幼虫活性。然而，阿维菌素毒性最高（LC₅₀ = 10.36 ppm），对（该种）幼虫死亡率有统计学显著影响，其次是多杀霉素（LC₅₀ = 21.32 ppm）和噻嗪酮（LC₅₀ = 56.34 ppm）。阿维菌素分别在处理后06小时和07小时导致幼虫死亡率在30.00%至53.33%和53.00 - 70.00%之间。就植物源药剂而言，麻疯树油（LC₅₀ = 216.61 ppm）比印楝油（LC₅₀ = 330.93 ppm）更具致死性（超过1.5倍）且致死时间更短，并显示出浓度与死亡率随时间变化的典型关系模式。总体而言，本研究突出了在蚊子病媒控制项目中部署新一代生物合理农药和植物源药剂的潜力。
