Memorial Sloan Kettering Cancer Center, New York, New York, USA
Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Osun State, Nigeria.
BMJ Open. 2024 Jun 4;14(6):e077154. doi: 10.1136/bmjopen-2023-077154.
To explore the gaps in the safe handling, administration, preparation and disposal of chemotherapy agents in low and middle-income countries.
Two surveys comprising a needs assessment survey and an American Cancer Society (ACS) ChemoSafe Facility Assessment.
2019 African Research Group for Oncology Symposium in South-West Nigeria (needs assessment) and the 2021 virtual engagement (ChemoSafe Assessment).
Health professionals (n=50 of 98) from multiple institutions across Nigeria (needs assessment survey) and a designated task force of health professionals (n=10) from one teaching hospital in Southwest Nigeria(ChemoSafe Facility Assessment).
In 2019, 75% of survey respondents (n=50) reported a lack of training resources for safe handling of chemotherapy. Additionally, 61% felt dissatisfaction with assessment practices for preparing and administering chemotherapy. ChemoSafe is a programme developed by the ACS to assess the ability of a facility to handle hazardous drugs. The 2021 ACS ChemoSafe survey administered at one teaching hospital indicated several areas for improvement to promote concordance with international standards for safe handling. Thirty-three (19.5%) items received a 'Yes' response (ie, met compliance with international standards).
There is a need for the implementation of training resources for handling, administering and disposing of chemotherapy at sites across Nigeria. Strategies to identify and prioritise areas of need must be implemented in the context of available resources.
探索中低收入国家在化疗药物安全处理、管理、准备和处置方面存在的差距。
两项调查，包括需求评估调查和美国癌症协会（ACS）化疗安全设施评估。
2019 年在尼日利亚西南部举行的非洲肿瘤研究组研讨会（需求评估）和 2021 年虚拟会议（化疗安全评估）。
来自尼日利亚多家机构的卫生专业人员（98 人中有 50 人参加了需求评估调查）和来自西南部一家教学医院的指定卫生专业人员工作队（10 人参加了化疗安全设施评估）。
2019 年，75%的调查受访者（n=50）报告缺乏安全处理化疗的培训资源。此外，61%的人对准备和管理化疗的评估实践不满意。化疗安全是美国癌症协会开发的一个方案，用于评估一个设施处理危险药物的能力。在一家教学医院进行的 2021 年美国癌症协会化疗安全调查显示，为了促进与安全处理的国际标准一致，有几个需要改进的领域。有 33 个（19.5%）项目的答复为“是”（即符合国际标准）。
尼日利亚各地需要实施化疗处理、管理和处置方面的培训资源。必须根据现有资源确定和确定优先需求领域的战略。
