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全胸腔镜双瓣膜置换术的技术与早期疗效

Technique and early outcomes of total thoracoscopic double-valve replacement.

作者信息

Chen Bo, Wang Tao, Xu Zheng, Zheng Zi-He, Wang Wei, Jiang Xin, Dai Xiao-Fu

机构信息

Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, China.

Key Laboratory of Cardio-Thoracic Surgery (Fujian Medical University), Fuzhou, China.

出版信息

JTCVS Tech. 2024 Feb 4;24:41-49. doi: 10.1016/j.xjtc.2024.01.019. eCollection 2024 Apr.

Abstract

OBJECTIVE

Reports on aortic and mitral double-valve replacement through total thoracoscopy are scarce, with surgical techniques constantly evolving. We aimed to compare the feasibility and safety between total thoracoscopic double-valve replacement and median sternotomy double-valve replacement.

METHODS

From November 2021 to March 2023, we performed double-valve replacements in 76 patients using the total thoracoscopic double-valve replacement. The control group comprised 77 patients who underwent median sternotomy double-valve replacement. We analyzed data on baseline characteristics, perioperative events, and early postoperative outcomes.

RESULTS

In the total thoracoscopic double-valve replacement group, the cardiopulmonary bypass and aortic crossclamping times were 174.20 ± 38.87 minutes and 120.20 ± 19.54 minutes, respectively; both were significantly longer compared with those in the median sternotomy double-valve replacement group (cardiopulmonary bypass: 123.65 ± 15.33 minutes; aortic crossclamping: 82.86 ± 9.51 minutes,  < .001). The total thoracoscopic double-valve replacement group exhibited an extended operative duration, with a mean of 4.40 ± 0.76 hours, in contrast to 3.21 ± 0.68 hours in the median sternotomy double-valve replacement group ( < .001). Postoperatively, the total thoracoscopic double-valve replacement group demonstrated a significantly shorter mechanical ventilation duration (9.29 ± 3.12 hours) and reduced intensive care unit stay time (24.31 ± 7.29 hours) than the median sternotomy double-valve replacement group (11.49 ± 4.27 hours and 26.76 ± 5.89 hours, respectively; values of .019 and .040, respectively). Furthermore, the total thoracoscopic double-valve replacement group experienced a shorter postoperative hospitalization time, averaging 6.21 ± 1.58 days, than the median sternotomy double-valve replacement group (8.35 ± 1.07 days,  < .001). The total thoracoscopic double-valve replacement group also exhibited significantly lower chest drainage volume (average 223.91 ± 53.93 mL) than the median sternotomy double-valve replacement group (382.56 ± 61.87 mL,  < .001). In terms of transfusion rates, the total thoracoscopic double-valve replacement group (9.21%) showed a marked reduction compared with the median sternotomy double-valve replacement group (36.36%,  < .001). Both groups had similar major complications.

CONCLUSIONS

The initial results of the total thoracoscopic double-valve replacement underscore its safety and efficacy. This approach extends the applicability of total thoracoscopic cardiac surgery and warrants deeper exploration.

摘要

目的

关于全胸腔镜下主动脉瓣和二尖瓣双瓣置换术的报道较少,且手术技术不断发展。我们旨在比较全胸腔镜双瓣置换术与正中开胸双瓣置换术的可行性和安全性。

方法

2021年11月至2023年3月,我们对76例患者实施了全胸腔镜双瓣置换术。对照组包括77例行正中开胸双瓣置换术的患者。我们分析了基线特征、围手术期事件及术后早期结果的数据。

结果

在全胸腔镜双瓣置换术组中,体外循环时间和主动脉阻断时间分别为174.20±38.87分钟和120.20±19.54分钟;与正中开胸双瓣置换术组相比均显著更长(体外循环:123.65±15.33分钟;主动脉阻断:82.86±9.51分钟,P<0.001)。全胸腔镜双瓣置换术组手术时间延长,平均为4.40±0.76小时,而正中开胸双瓣置换术组为3.21±0.68小时(P<0.001)。术后,全胸腔镜双瓣置换术组机械通气时间显著更短(9.29±3.12小时),重症监护病房停留时间缩短(24.31±7.29小时),低于正中开胸双瓣置换术组(分别为11.49±4.27小时和26.76±5.89小时;P值分别为 .019和.040)。此外,全胸腔镜双瓣置换术组术后住院时间更短,平均为6.21±1.58天,低于正中开胸双瓣置换术组(8.35±1.07天,P<0.001)。全胸腔镜双瓣置换术组胸腔引流量也显著更低(平均223.91±53.93 mL),低于正中开胸双瓣置换术组(382.56±61.87 mL,P<0.001)。在输血率方面,全胸腔镜双瓣置换术组(9.21%)与正中开胸双瓣置换术组(36.36%)相比显著降低(P<0.001)。两组主要并发症相似。

结论

全胸腔镜双瓣置换术的初步结果强调了其安全性和有效性。这种方法扩展了全胸腔镜心脏手术的适用性,值得深入探索。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f20/11145387/cc224f2477d2/fx1.jpg

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