Nukaly Houriah Y, Aljuhani Raghad A, Alhartani Mahinar M, Alhindi Yosra Z, Asif Uzma, Alshanberi Asim M, Alsanosi Safaa M
General Medicine Practice Program, Batterjee Medical College, Jeddah, Saudi Arabia.
Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
Adv Med Educ Pract. 2024 May 31;15:501-512. doi: 10.2147/AMEP.S462490. eCollection 2024.
The World Health Organization (WHO) has placed great importance on providing thorough, hands-on training to medical students regarding responsible and appropriate antibiotic prescription. Accordingly, this study aims to gain a better perspective on the knowledge of antibiotic use and resistance among medical students in Jeddah, Saudi Arabia.
A questionnaire-based cross-sectional study was conducted among medical students in Jeddah, Saudi Arabia, from 1 September to 30 November 2023. The categorical variables are presented as frequencies and percentages. Mann-Whitney and Kruskal-Wallis tests were used to compare the outcomes, and generalised linear regression models were constructed to predict the students' knowledge of antibiotics and antibiotic resistance. A p-value of < 0.05 was taken to indicate statistical significance.
The study included a total of 353 medical students. First-year medical students represented 28.60% of the participants, while females represented 76.80%. Most participants (92.40%) agreed that antibiotics are effective against bacteria, whereas only 25.20% agreed about antibiotics' effectiveness against viruses. More than half of the participants (53.80%) believed that bacterial infections can be resolved without antibiotics. A significant majority (78.20%) agreed that the unnecessary use of antibiotics makes them less effective. More than half of the participants (56.90%) acknowledged that infections caused by resistant bacteria are increasing in Saudi Arabia, and two-thirds (75.10%) believed that healthcare workers could effectively reduce antibiotic resistance in Saudi Arabia. Male students had low knowledge about antibiotics [Beta = -1.429, 95% CI (-2.618, -0.241), P value = 0.019].
Improving the curriculum by incorporating topics like resistance mechanisms and responsible antibiotic usage can address the knowledge gap among male students. This comprehensive training, utilizing various educational methods, is essential for fostering responsible antibiotic practices among future healthcare professionals.
世界卫生组织（WHO）高度重视为医学生提供关于合理、恰当使用抗生素的全面实践培训。因此，本研究旨在更好地了解沙特阿拉伯吉达医学生对抗生素使用和耐药性的认知情况。
2023年9月1日至11月30日，在沙特阿拉伯吉达的医学生中开展了一项基于问卷调查的横断面研究。分类变量以频率和百分比呈现。采用曼-惠特尼检验和克鲁斯卡尔-沃利斯检验比较结果，并构建广义线性回归模型来预测学生对抗生素和抗生素耐药性的认知。p值<0.05表示具有统计学意义。
该研究共纳入353名医学生。一年级医学生占参与者的28.60%，女性占76.80%。大多数参与者（92.40%）认为抗生素对细菌有效，而只有25.20%的人认为抗生素对病毒有效。超过一半的参与者（53.80%）认为细菌感染无需使用抗生素即可治愈。绝大多数（78.20%）的人认为不必要地使用抗生素会降低其有效性。超过一半的参与者（56.90%）承认沙特阿拉伯耐药菌引起的感染正在增加，三分之二（75.10%）的人认为医护人员可以有效降低沙特阿拉伯的抗生素耐药性。男学生对抗生素的了解较少[β=-1.429，95%置信区间（-2.618，-0.241），P值=0.019]。
通过纳入耐药机制和合理使用抗生素等主题来改进课程设置，可以弥补男学生的知识差距。这种利用多种教育方法的全面培训对于培养未来医护人员合理使用抗生素的习惯至关重要。
