Alowfi Areej, Alghamdi Rana, Albogami Dhai, Bukhari Laila, Khan Muhammad Anwar, Almarhoumi Lujain
Family Medicine and Primary Health Care Department, Ministry of the National Guard-Health Affairs, Jeddah, Saudi Arabia.
College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Saudi Pharm J. 2023 Jan;31(1):55-64. doi: 10.1016/j.jsps.2022.11.005. Epub 2022 Nov 14.
Antibiotic resistance (ABR) is defined as bacteria's resistance to therapy despite therapeutic levels of antibiotics. It is a global health concern. Data on the antibiotic prescription practice of physicians, in general, are limited in Saudi Arabia. Therefore, we aim to assess the knowledge, attitude, and practice of antibiotic prescription between surgical and non-surgical residents at King Abdulaziz Medical City (KAMC).
A cross-sectional study was conducted at KAMC in Jeddah, Saudi Arabia, from September 2019, until March 2020. The questionnaire contained demographic information and 31 questions based on the studied variables: knowledge (17), attitude (4), and practice (10).
The response rate was 83 %. Male to female response rates were 54 % and 46 %, respectively. The majority of respondents (72 %) were non-surgical residents. Positive practice skills showed that 55 % of all healthcare residents always used practice guidelines for antibiotic prescription in their daily work (P-value < 0.001). Most residents (50 %) sometimes used delayed prescriptions. Non-surgical residents discussed ABR with patients more than surgical residents (P-value = 0.028). Lack of patient interest was the common cause for not discussing ABR with patients (42 %). Non-surgical residents had significantly more training on antibiotic prescription (p-value = 0.001). The fear of infection spread due to not prescribing an antibiotic was significantly higher in non-surgical residents (P-value < 0.001). Non-surgical residents (76 %) took a past medical history of antibiotic consumption more than surgical residents (24 %) (P-value = 0.003). Antibiotic prescription for residents was not influenced by advertisements (91 %). The most common resistant organisms reported by residents were insignificant between the two groups. The results also showed that the residents' common choice of antibiotics was not statistically different between surgical and non-surgical residents in most antibiotic classes.
We found that practice guidelines, formal training, and taking patients' past medical histories were significantly higher among non-surgical residents. In contrast, surgical residents were prescribing more antibiotics due to the fear of the spread of the infection. Proper training is essential for all healthcare residents to overcome differences among different specialties.
抗生素耐药性（ABR）被定义为尽管达到治疗水平的抗生素治疗，但细菌仍具有耐药性。这是一个全球健康问题。总体而言，沙特阿拉伯关于医生抗生素处方实践的数据有限。因此，我们旨在评估阿卜杜勒阿齐兹国王医疗城（KAMC）外科和非外科住院医师在抗生素处方方面的知识、态度和实践。
2019年9月至2020年3月在沙特阿拉伯吉达的KAMC进行了一项横断面研究。问卷包含人口统计学信息以及基于研究变量的31个问题：知识（17个）、态度（4个）和实践（10个）。
回复率为83%。男性和女性的回复率分别为54%和46%。大多数受访者（72%）是非外科住院医师。积极的实践技能表明，所有医疗保健住院医师中有55%在日常工作中始终使用抗生素处方实践指南（P值<0.001）。大多数住院医师（50%）有时会使用延迟处方。非外科住院医师比外科住院医师更常与患者讨论抗生素耐药性（P值 = 0.028）。患者缺乏兴趣是不与患者讨论抗生素耐药性的常见原因（42%）。非外科住院医师接受的抗生素处方培训明显更多（p值 = 0.001）。非外科住院医师因不开抗生素而担心感染传播的情况明显更高（P值<0.001）。非外科住院医师（76%）比外科住院医师（24%）更常询问患者过去的抗生素使用病史（P值 = 0.003）。住院医师的抗生素处方不受广告影响（91%）。两组住院医师报告的最常见耐药菌无显著差异。结果还表明，在大多数抗生素类别中，外科和非外科住院医师对抗生素的常见选择在统计学上没有差异。
我们发现非外科住院医师在实践指南、正规培训和询问患者过去病史方面明显更高。相比之下，外科住院医师由于担心感染传播而开具更多抗生素。适当的培训对于所有医疗保健住院医师克服不同专业之间的差异至关重要。
