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面外恶性雀斑痣:一种进展模型和使用皮肤镜和反射共聚焦显微镜增强的诊断技术。

Extrafacial lentigo maligna: A progression model and enhanced diagnostic techniques using dermatoscopy and reflectance confocal microscopy.

机构信息

Hospital Universitario Fundación Alcorcón, Alcorcón, Spain.

出版信息

J Cutan Pathol. 2024 Sep;51(9):672-679. doi: 10.1111/cup.14665. Epub 2024 Jun 5.

Abstract

Lentigo maligna (LM) is a subtype of lentiginous melanoma confined to the epidermis, which is associated with chronic sun exposure. Its clinical, dermatoscopic, and histopathological diagnosis can be challenging, particularly in the early and advanced stages, requiring appropriate clinicopathological correlation. This article reviews the clinical presentation, diagnosis through noninvasive methods (dermoscopy and confocal microscopy), and provides insights for diagnosis of extrafacial LM through the presentation of four representative clinical cases from different phases of a theoretical-practical progression model. Recognizing these lesions is crucial, as once they invade the dermis, they can behave like any other type of melanoma.

摘要

恶性雀斑样痣(LM)是局限于表皮的雀斑样黑素瘤的一个亚型,与慢性日光暴露有关。其临床、皮肤镜和组织病理学诊断具有挑战性,特别是在早期和晚期,需要适当的临床病理相关性。本文回顾了临床表现,通过非侵入性方法(皮肤镜和共聚焦显微镜)进行诊断,并通过从理论-实践进展模型的不同阶段呈现四个具有代表性的临床病例,为面部以外的 LM 诊断提供了见解。识别这些病变至关重要,因为一旦它们侵犯真皮,它们的行为就可能与任何其他类型的黑色素瘤一样。

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