Abdel Baky Ashraf, Al Refaei Ashraf, El Melegy Ebtesam, Tantawi Hayam, Mansour Lobna, Mohamed Moustafa, El Rashidy Omnia, Hassanein Sahar, Omar Tarek, Elsayeh Abdelsattar, ElGazzar Hammouda, Amer Yasser Sami, Abd Elmaksoud Marwa
Pediatrics Department, Ain Shams University, Cairo, Egypt; Pediatrics Department, Armed Forces College of Medicine (AFCM), Cairo, Egypt.
Child Health and Pediatric Neurology, National Research Center, Cairo, Egypt.
Pediatr Neurol. 2024 Aug;157:14-18. doi: 10.1016/j.pediatrneurol.2024.05.004. Epub 2024 May 10.
The presented evidence-based clinical practice guideline (CPG) is proposed as a National CPG where we adapted the international recommendations for the emergency management of seizures in children beyond the neonatal period to suit the health care in Egypt. The quality of evidence and the strength of recommendations are indicated. This study aimed to standardize the treatment of acute epileptic seizures and to provide an easy-to-apply acute treatment protocol that will allow immediate and appropriate seizure control.
This is part of a larger program by the Egyptian Pediatric Clinical Practice Guidelines Committee (EPG) in collaboration with the staff of pediatric departments of 15 Egyptian universities and the National Research Centre. EPG was affiliated later to the Supreme Council of the Egyptian University Hospitals aiming to define the topics of, assign authors to, and assist in the adaptation of pediatric evidence-based CPGs according to a national strategic plan (http://epg.edu.eg). The committee is guided by a formal CPG adaptation methodology: the "Adapted ADAPTE."
The Egyptian Childhood Seizure Group (ECSG) reviewed the results of the Appraisal of Guidelines for Research and Evaluation II assessment and decided to adapt the recommendations of three source CPGs: American Epilepsy Society, Italian League Against Epilepsy, Neurocritical Care Society, and Neurologic & Psychiatric Society of Zambia. Eight implementation tools were included. A comprehensive set of multifaceted CPG implementation strategies was provided for the clinicians, patients, nurses, and other relevant stakeholders contextualized to the national settings.
Our experience with this adaptation methodology provides useful insight into its national utilization in Egypt.
本循证临床实践指南（CPG）被提议作为国家CPG，我们对新生儿期以后儿童癫痫发作的国际急诊管理建议进行了调整，以适应埃及的医疗保健情况。文中指出了证据质量和推荐强度。本研究旨在规范急性癫痫发作的治疗，并提供一个易于应用的急性治疗方案，以实现癫痫发作的即时和适当控制。
这是埃及儿科临床实践指南委员会（EPG）与埃及15所大学儿科部门工作人员及国家研究中心合作开展的一个更大项目的一部分。EPG后来隶属于埃及大学医院最高委员会，旨在根据国家战略计划（http://epg.edu.eg）确定儿科循证CPG的主题、指定作者并协助进行调整。该委员会遵循正式的CPG调整方法：“改编后的ADAPTE”。
埃及儿童癫痫发作小组（ECSG）审查了《研究与评价指南II》评估的结果，并决定采用三个来源CPG的建议：美国癫痫协会、意大利抗癫痫联盟、神经重症监护协会以及赞比亚神经与精神学会。其中包括八个实施工具。针对临床医生、患者、护士及其他相关利益攸关方，结合国家实际情况提供了一套全面的多方面CPG实施策略。
我们在这种调整方法方面的经验为其在埃及的全国应用提供了有益的见解。
