Larkin J G, Capell H A, Sturrock R D
Ann Rheum Dis. 1985 Mar;44(3):199-201. doi: 10.1136/ard.44.3.199.
Thirty-five patients with rheumatoid arthritis were randomly allocated to either Seatone (green-lipped mussel extract) or placebo in order to assess the former's claimed effectiveness in rheumatoid disease. After six months there was no significant improvement in any laboratory or clinical measurement of disease activity in the Seatone group. The patients on active drug fared no better than those on placebo. These results suggest that Seatone is not effective in rheumatoid arthritis.
35名类风湿性关节炎患者被随机分为两组，分别服用Seatone（绿唇贻贝提取物）或安慰剂，以评估前者对类风湿疾病所宣称的疗效。六个月后，Seatone组在疾病活动的任何实验室或临床测量指标上均未出现显著改善。服用活性药物的患者与服用安慰剂的患者情况并无差异。这些结果表明，Seatone对类风湿性关节炎无效。
