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神经心脏病学。80年代的一个跨学科领域。

Neurocardiology. An interdisciplinary area for the 80s.

作者信息

Natelson B H

出版信息

Arch Neurol. 1985 Feb;42(2):178-84. doi: 10.1001/archneur.1985.04060020096022.

DOI:10.1001/archneur.1985.04060020096022
PMID:3883960
Abstract

This review focuses on the relations between neural structures and the heart in the pathogenesis of severe cardiac dysfunction (namely, cardiac arrhythmias, focal cardiac lesions, and the sudden death syndrome). After establishing the anatomic connections between the brain and the heart and then reviewing ways to assess the integrity of nerves to the heart, the clinical literature relating human brain dysfunction to cardiologic problems is reviewed. Next the experimental literature is briefly reviewed. The organization of the information is based on whether or not the heart of the experimental animal is normal as well as on the part of the nervous system involved (ie, either central or peripheral). In addition, since the effect of environmental stress on cardiac dysfunction must be modulated via the brain, the review is briefly extended to examine the role of stress in the production of severe cardiac dysfunction in people as well as animals.

摘要

本综述聚焦于严重心脏功能障碍(即心律失常、局灶性心脏病变和猝死综合征)发病机制中神经结构与心脏之间的关系。在确立大脑与心脏之间的解剖学联系,然后回顾评估心脏神经完整性的方法之后,对将人类脑功能障碍与心脏问题相关联的临床文献进行了综述。接下来简要回顾了实验文献。信息的组织基于实验动物的心脏是否正常以及所涉及的神经系统部分(即中枢或外周)。此外,由于环境应激对心脏功能障碍的影响必须通过大脑进行调节,因此本综述简要扩展至探讨应激在人类和动物严重心脏功能障碍产生中的作用。

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