• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

胚胎过剩:对全球性挑战的批判性视角。

Too many embryos: a critical perspective on a global challenge.

机构信息

Obstetrics and Gynaecology Unit, IRCCS San Raffaele Scientific Institute, Via Olgettina, 60, Milan, 20132, Italy.

Reproductive Sciences Laboratory, Obstetrics and Gynaecology Unit, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milan, 20132, Italy.

出版信息

J Assist Reprod Genet. 2024 Jul;41(7):1821-1824. doi: 10.1007/s10815-024-03159-w. Epub 2024 Jun 5.

DOI:10.1007/s10815-024-03159-w
PMID:38839697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11263306/
Abstract

Over the past decade, significant endeavors have been directed toward establishing an optimal oocyte number to maximize the chances for successful in vitro fertilization outcomes. The effectiveness of assisted reproductive technologies has greatly improved, and more good-quality embryos are being created in each cycle. However, many of these embryos remain unused. Notably, in Europe, approximately one-third of couples did not use their surplus cryopreserved embryos. Surplus embryos pose a challenge for patients and clinics. Embryo disposal practices are not the same all over the continent, with embryo donation and embryo discharge not allowed in several countries. In this scenario, limiting the number of surplus embryos by reducing the number of inseminated oocytes, according to couple clinical history, could be a strategy.

摘要

在过去的十年中,人们做出了巨大的努力来确定最佳的卵母细胞数量,以最大限度地提高体外受精的成功率。辅助生殖技术的有效性有了很大的提高,每个周期都能产生更多的优质胚胎。然而,其中许多胚胎仍然未被使用。值得注意的是,在欧洲,大约有三分之一的夫妇没有使用他们多余的冷冻胚胎。多余的胚胎对患者和诊所来说都是一个挑战。胚胎处理方式在整个欧洲大陆并不相同,一些国家不允许胚胎捐赠和胚胎丢弃。在这种情况下,根据夫妇的临床病史,通过减少授精卵母细胞的数量来限制多余胚胎的数量可能是一种策略。

相似文献

1
Too many embryos: a critical perspective on a global challenge.胚胎过剩:对全球性挑战的批判性视角。
J Assist Reprod Genet. 2024 Jul;41(7):1821-1824. doi: 10.1007/s10815-024-03159-w. Epub 2024 Jun 5.
2
Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance.辅助生殖技术中卵母细胞、胚胎和囊胚冷冻保存:比较慢速冷冻与玻璃化冷冻的系统评价和荟萃分析,为制定全球指南提供证据。
Hum Reprod Update. 2017 Mar 1;23(2):139-155. doi: 10.1093/humupd/dmw038.
3
A randomized controlled trial comparing embryo vitrification with slush nitrogen to liquid nitrogen in women undergoing frozen embryo transfer: embryology and clinical outcomes.一项针对接受冻融胚胎移植的女性,比较胚胎玻璃化冷冻使用半融氮与液氮的随机对照试验:胚胎学及临床结局
Hum Reprod. 2025 Mar 1;40(3):426-433. doi: 10.1093/humrep/deaf003.
4
Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes.为接受冻融胚胎或供体卵母细胞来源胚胎移植的女性进行子宫内膜准备。
Cochrane Database Syst Rev. 2010 Jan 20(1):CD006359. doi: 10.1002/14651858.CD006359.pub2.
5
Embryo freezing for preventing Ovarian Hyperstimulation Syndrome.胚胎冷冻以预防卵巢过度刺激综合征。
Cochrane Database Syst Rev. 2002(2):CD002806. doi: 10.1002/14651858.CD002806.
6
Number of embryos for transfer following in-vitro fertilisation or intra-cytoplasmic sperm injection.体外受精或卵胞浆内单精子注射后移植的胚胎数量。
Cochrane Database Syst Rev. 2004 Oct 18(4):CD003416. doi: 10.1002/14651858.CD003416.pub2.
7
Fresh versus frozen embryo transfers in assisted reproduction.辅助生殖中新鲜胚胎移植与冷冻胚胎移植的比较。
Cochrane Database Syst Rev. 2017 Mar 28;3(3):CD011184. doi: 10.1002/14651858.CD011184.pub2.
8
Cleavage-stage versus blastocyst-stage embryo transfer in assisted reproductive technology.卵裂期胚胎与囊胚期胚胎在辅助生殖技术中的移植。
Cochrane Database Syst Rev. 2022 May 19;5(5):CD002118. doi: 10.1002/14651858.CD002118.pub6.
9
Embryo freezing for preventing ovarian hyperstimulation syndrome.胚胎冷冻以预防卵巢过度刺激综合征。
Cochrane Database Syst Rev. 2007 Jul 18;2007(3):CD002806. doi: 10.1002/14651858.CD002806.pub2.
10
Is frozen embryo transfer better for mothers and babies? Can cumulative meta-analysis provide a definitive answer?冻融胚胎移植对母亲和婴儿更好吗?累积荟萃分析能否给出明确答案?
Hum Reprod Update. 2018 Jan 1;24(1):35-58. doi: 10.1093/humupd/dmx031.

引用本文的文献

1
Embryo Cryopreservation: What do couples think about it?胚胎冷冻保存:夫妻对此有何看法?
JBRA Assist Reprod. 2025 Mar 12;29(1):94-102. doi: 10.5935/1518-0557.20240093.

本文引用的文献

1
An egg is not a chicken and an embryo is not a child.鸡蛋不是鸡,胚胎也不是儿童。
Fertil Steril. 2024 May;121(5):752-753. doi: 10.1016/j.fertnstert.2024.03.013. Epub 2024 Mar 18.
2
Estimating the number of oocytes to expose to sperm in assisted reproductive technology treatment.估算辅助生殖技术治疗中与精子接触的卵母细胞数量。
Fertil Steril. 2024 Jun;121(6):1063-1065. doi: 10.1016/j.fertnstert.2024.02.039. Epub 2024 Feb 23.
3
Towards a more sustainable balance between optimal live birth rate and supernumerary embryos in ART treatments.在辅助生殖技术治疗中,寻求更可持续的最佳活产率和多余胚胎之间的平衡。
J Assist Reprod Genet. 2024 Apr;41(4):939-946. doi: 10.1007/s10815-024-03043-7. Epub 2024 Feb 7.
4
ART in Europe, 2019: results generated from European registries by ESHRE†.ART 在欧洲,2019:ESHRE 通过欧洲注册中心生成的结果。
Hum Reprod. 2023 Dec 4;38(12):2321-2338. doi: 10.1093/humrep/dead197.
5
ART and the forgotten siblings: a call for research.艺术与被遗忘的兄弟姐妹:呼吁开展研究。
Hum Reprod. 2023 Jul 5;38(7):1235-1238. doi: 10.1093/humrep/dead082.
6
A higher number of oocytes retrieved is associated with an increase in fertilized oocytes, blastocysts, and cumulative live birth rates.取到的卵母细胞数量越多,受精的卵母细胞、胚胎和累积活产率就越高。
Fertil Steril. 2023 May;119(5):762-769. doi: 10.1016/j.fertnstert.2023.01.001. Epub 2023 Jan 10.
7
Development of a Model to Estimate the Optimal Number of Oocytes to Attempt to Fertilize During Assisted Reproductive Technology Treatment.制定模型估算辅助生殖技术治疗中尝试受精的最佳卵母细胞数量。
JAMA Netw Open. 2023 Jan 3;6(1):e2249395. doi: 10.1001/jamanetworkopen.2022.49395.
8
Delayed blastocyst development is influenced by the level of progesterone on the day of trigger.囊胚发育迟缓受扳机日孕酮水平的影响。
J Assist Reprod Genet. 2023 Feb;40(2):361-370. doi: 10.1007/s10815-022-02682-y. Epub 2022 Dec 21.
9
Embryo cryopreservation and utilization in the United States from 2004-2013.2004年至2013年美国的胚胎冷冻保存与利用情况
F S Rep. 2020 Sep 28;1(2):71-77. doi: 10.1016/j.xfre.2020.05.010. eCollection 2020 Sep.
10
Fertilization rate as a novel indicator for cumulative live birth rate: a multicenter retrospective cohort study of 9,394 complete in vitro fertilization cycles.受精率作为累积活产率的新指标:一项对 9394 个完整体外受精周期的多中心回顾性队列研究。
Fertil Steril. 2021 Sep;116(3):766-773. doi: 10.1016/j.fertnstert.2021.04.006. Epub 2021 May 8.