College of Veterinary Medicine, Large Animal Clinical Sciences, The University of Tennessee, Knoxville, Tennessee, USA.
Tickle College of Engineering, Mechanical, Aerospace and Biomedical Engineering, The University of Tennessee, Knoxville, Tennessee, USA.
Vet Surg. 2024 Oct;53(7):1161-1172. doi: 10.1111/vsu.14115. Epub 2024 Jun 5.
To assess a three-dimensional (3-D)-printed laryngeal clamp (LC) designed to enhance the anchoring of laryngeal prostheses at the cricoid cartilage.
Ex vivo biomechanical study.
A total of 22 equine larynges.
Two experimental groups included larynges with standard prosthetic laryngoplasty (PL; n = 10) and larynges with prosthetic laryngoplasty modified with laryngeal clamps (PLLC; n = 10). All constructs underwent 3000 cycles of tension loading and a single tension to failure. Recorded biomechanical parameters included maximum load, actuator displacement, and construct failure. Finite element analysis (FEA) was performed on one PL and one PLLC construct.
The maximum load at single tension to failure was 183.7 ± 46.8 N for the PL construct and 292.7 ± 82.3 N for the PLLC construct (p = .003). Actuator displacement at 30 N was 1.7 ± 0.5 mm and 2.7 ± 0.7 mm for the PL and PLLC constructs, respectively (p = .011). The cause of PL constructs failure was mostly tearing through the cartilage whereas the PLLC constructs failed through fracture of the cricoid cartilage (p = .000). FEA revealed an 11-fold reduction in the maximum equivalent plastic strain, a four-fold reduction in maximum compressive stress, and a two-fold increase in the volume of engaged cartilage in PLLC constructs.
The PLLC constructs demonstrated superior performance in biomechanical testing and FEA compared to standard PL constructs.
The use of 3-D-printed laryngeal clamps may enhance the outcomes of laryngoplasty in horses. In vivo studies are necessary to determine the feasibility of performing laryngoplasty using the laryngeal clamp in horses.
评估一种三维（3-D）打印喉夹（LC），旨在增强环状软骨处喉假体的锚固。
体外生物力学研究。
总共 22 个马喉。
两组实验均包括行标准喉成形术（PL）的喉（n=10）和行改良喉夹喉成形术（PLLC）的喉（n=10）。所有构建体均经历 3000 次张力加载循环和单次张力失效测试。记录的生物力学参数包括最大负荷、执行器位移和构建体失效。对一个 PL 和一个 PLLC 构建体进行有限元分析（FEA）。
PL 构建体的单次张力失效的最大负荷为 183.7±46.8N，PLLC 构建体的最大负荷为 292.7±82.3N（p=0.003）。在 30N 时，PL 和 PLLC 构建体的执行器位移分别为 1.7±0.5mm 和 2.7±0.7mm（p=0.011）。PL 构建体的失效原因主要是软骨撕裂，而 PLLC 构建体则是环状软骨骨折（p=0.000）。FEA 显示，最大等效塑性应变降低了 11 倍，最大压缩应力降低了 4 倍，参与的软骨体积增加了 2 倍。
与标准 PL 构建体相比，PLLC 构建体在生物力学测试和 FEA 中表现出更好的性能。
3-D 打印喉夹的使用可能会提高马喉成形术的效果。有必要进行体内研究，以确定在马中使用喉夹进行喉成形术的可行性。
