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开放性胫骨骨折后骨髓炎的防治

Prevention and treatment of osteomyelitis after open tibia fractures.

作者信息

Mehta Devan D, Leucht Philipp

机构信息

Department of Orthopedic Surgery, NYU Grossman School of Medicine-NYU Langone Orthopedic Hospital, New York, NY.

出版信息

OTA Int. 2024 Jun 5;7(4 Suppl):e309. doi: 10.1097/OI9.0000000000000309. eCollection 2024 Jun.

DOI:10.1097/OI9.0000000000000309
PMID:38840709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11149744/
Abstract

Infection and chronic post-traumatic osteomyelitis of the tibia after open fracture are complex problems that cause significant morbidity and threaten the viability of a limb. Therefore, it is of utmost importance for the orthopaedic surgeon to understand both patient and treatment factors that modify the risk of developing these disastrous complications. Infection risk is largely based on severity of open injury in addition to inherent patient factors. Orthopaedic surgeons can work to mitigate this risk with prompt antibiotic administration, thorough and complete debridement, expedient fracture stabilization, and early wound closure. In the case osteomyelitis does occur, the surgeon should use a systematic multidisciplinary approach for eradication.

摘要

开放性骨折后胫骨感染及慢性创伤后骨髓炎是复杂问题,会导致严重发病并威胁肢体存活。因此,骨科医生了解影响发生这些灾难性并发症风险的患者因素和治疗因素至关重要。除患者固有因素外,感染风险很大程度上取决于开放性损伤的严重程度。骨科医生可通过及时给予抗生素、彻底清创、迅速稳定骨折及早期闭合伤口来降低此风险。若确实发生骨髓炎,外科医生应采用系统的多学科方法进行根除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0282/11149744/cc185e2f7a1a/oi9-7-e309-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0282/11149744/7e509f086a45/oi9-7-e309-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0282/11149744/cc185e2f7a1a/oi9-7-e309-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0282/11149744/7e509f086a45/oi9-7-e309-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0282/11149744/cc185e2f7a1a/oi9-7-e309-g002.jpg

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本文引用的文献

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Where Are We in 2022? A Summary of 11,000 Open Tibia Fractures Over 4 Decades.2022 年我们处于什么位置?40 年来 11000 例开放性胫骨骨折的总结。
J Orthop Trauma. 2023 Aug 1;37(8):e326-e334. doi: 10.1097/BOT.0000000000002602.
2
Fracture Related Infections and Their Risk Factors for Treatment Failure-A Major Trauma Centre Perspective.骨折相关感染及其治疗失败的危险因素——来自一家大型创伤中心的视角
Diagnostics (Basel). 2022 May 22;12(5):1289. doi: 10.3390/diagnostics12051289.
3
Arterial Injury Portends Worse Soft Tissue Outcomes and Delayed Coverage in Open Tibial Fractures.
动脉损伤预示着开放性胫骨骨折的软组织预后更差和延迟覆盖。
J Orthop Trauma. 2022 Oct 1;36(10):535-543. doi: 10.1097/BOT.0000000000002372.
4
Surgical timing for open fractures: Middle of the night or the light of day, which fractures, what time?开放性骨折的手术时机:午夜还是白昼,何种骨折,何时手术?
OTA Int. 2020 Mar 23;3(1):e067. doi: 10.1097/OI9.0000000000000067. eCollection 2020 Mar.
5
Single-stage treatment of chronic localized tibial osteomyelitis with local debridement and antibiotic-loaded calcium sulfate implantation: a retrospective study of 42 patients.一期病灶清除联合载抗生素硫酸钙植入治疗慢性局限性胫骨骨髓炎:42 例回顾性研究。
J Orthop Surg Res. 2020 Jun 1;15(1):201. doi: 10.1186/s13018-020-01721-7.
6
Comparative accuracy assessment of the Gustilo and Tscherne classification systems as predictors of infection in open fractures.比较Gustilo和Tscherne分类系统作为开放性骨折感染预测指标的准确性评估
Rev Bras Ortop. 2018 Apr 4;53(3):314-318. doi: 10.1016/j.rboe.2018.03.005. eCollection 2018 May-Jun.
7
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