Meretsky Christopher R, Schiuma Anthony T
Surgery, St. George's University School of Medicine, Great River, USA.
Orthopedic Surgery, Holy Cross Health, Fort Lauderdale, USA.
Cureus. 2024 May 5;16(5):e59693. doi: 10.7759/cureus.59693. eCollection 2024 May.
Skin cancer is one of the most common types of cancer worldwide, and it can affect people of all ages, races, and genders. Mohs micrographic surgery (MMS), a specialized type of skin cancer surgery, boasts the highest cure rates for various types of skin malignancies. Slow Mohs surgery (SMS) is a methodical and meticulous approach to MMS that involves careful and deliberate examination of tissue samples to ensure the complete removal of skin cancer while preserving as much healthy tissue as possible. Both SMS and MMS have been indicated to be effective treatment options for skin cancer, depending on the type and stage of cancer. This case-control study analysis compares the efficacy of SMS for melanoma with that of MMS for squamous cell carcinoma (SCC) and basal cell carcinoma (BCC). We analyzed data from the past two decades to assess recurrence rates and treatment-related complications. Our findings suggest that SMS for melanoma achieves comparable outcomes to MMS in SCC and BCC. Both approaches demonstrated similar cure rates and complication profiles. However, further prospective studies are necessary to solidify these findings and refine the specific role of SMS in melanoma therapy.
皮肤癌是全球最常见的癌症类型之一，它可影响所有年龄、种族和性别的人群。莫氏显微外科手术（MMS）是一种专门的皮肤癌手术，对各种类型的皮肤恶性肿瘤具有最高的治愈率。慢速莫氏手术（SMS）是一种针对MMS的有条不紊且细致入微的方法，它涉及对组织样本进行仔细且审慎的检查，以确保在尽可能保留健康组织的同时彻底切除皮肤癌。根据癌症的类型和阶段，SMS和MMS均被证明是皮肤癌的有效治疗选择。本病例对照研究分析比较了SMS治疗黑色素瘤与MMS治疗鳞状细胞癌（SCC）和基底细胞癌（BCC）的疗效。我们分析了过去二十年的数据，以评估复发率和与治疗相关的并发症。我们的研究结果表明，用于黑色素瘤的SMS在SCC和BCC中取得了与MMS相当的结果。两种方法都显示出相似的治愈率和并发症情况。然而，需要进一步的前瞻性研究来巩固这些发现，并明确SMS在黑色素瘤治疗中的具体作用。
