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激光治疗与其他治疗甲癣方法的疗效比较:一项系统评价和荟萃分析

Efficacy of Laser Therapy in Comparison With Other Methods for the Treatment of Onychomycosis: A Systematic Review and Meta-Analysis.

作者信息

Meretsky Christopher R, Friday Brooke L, Schiuma Anthony T

机构信息

Surgery, St. George's University School of Medicine, Great River, USA.

Medical School, St. George's University School of Medicine, Great River, USA.

出版信息

Cureus. 2024 May 6;16(5):e59720. doi: 10.7759/cureus.59720. eCollection 2024 May.

Abstract

Onychomycosis, a fungal infection of the nails, presents a significant challenge in clinical management due to its chronic nature and resistance to conventional therapies. This study aims to evaluate the efficacy of laser therapy in treating onychomycosis compared to traditional methods such as terbinafine. A systematic review and meta-analysis were conducted to analyze existing literature on the subject. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) diagram illustrates the selection process of studies. Findings suggest that laser therapy demonstrates promising results in the treatment of onychomycosis, with comparable efficacy to terbinafine and fewer adverse effects. Further large-scale randomized controlled trials are warranted to validate these findings and establish laser therapy as a standard treatment option for onychomycosis.

摘要

甲癣,一种指甲的真菌感染,由于其慢性病程和对传统疗法的耐药性,在临床管理中构成了重大挑战。本研究旨在评估与特比萘芬等传统方法相比,激光疗法治疗甲癣的疗效。进行了一项系统评价和荟萃分析,以分析关于该主题的现有文献。系统评价和荟萃分析的首选报告项目(PRISMA)流程图说明了研究的选择过程。研究结果表明,激光疗法在治疗甲癣方面显示出有前景的结果,其疗效与特比萘芬相当,且不良反应较少。有必要进行进一步的大规模随机对照试验,以验证这些发现,并将激光疗法确立为甲癣的标准治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ac4/11151181/e9852bca44c3/cureus-0016-00000059720-i01.jpg

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