Jaradat Jaber H, Alkhawaldeh Ibraheem M, Nashwan Abdulqadir J, Al-Bojoq Yousef, Ramadan Monther N, Albalkhi Ibrahem
School of Medicine, Mutah University, Al Karak, JOR.
Department of Nursing, Hamad Medical Corporation, Doha, QAT.
Cureus. 2024 May 5;16(5):e59706. doi: 10.7759/cureus.59706. eCollection 2024 May.
Cerebellar hydatid cysts are uncommon lesions, with limited cases reported in the literature. This systematic review aimed to summarize current diagnostic and management approaches, given the low suspicion index of hydatid cysts in the cerebellum. The review was registered in the International Prospective Register of Systematic Reviews (PROSPERO) under registration number CRD42023437853. This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA-P) reporting guidelines. Two independent researchers searched PubMed, Scopus, and Google Scholar databases on June 27, 2023. We included 15 studies published between 1965 and 2022, comprising 12 case reports and three case series. A pooled analysis of reported cases (nine females and seven males) with cerebellar hydatid cysts revealed a mean age of 24 ± 20 years. Most of the cases were reported in Turkish hospitals ( = 8). The prominent signs and symptoms observed were headaches (10, 62.5%), ataxic gait (9, 56.25%), and visual disturbances (9, 56.25%). The time from symptom onset to hospital visit varied, with most patients seeking medical attention within the first three months. The left cerebellar hemisphere was the most common location of the cysts (6, 37.5%), and compression of the fourth ventricle was frequently observed. Computed tomography (CT) and magnetic resonance imaging (MRI) were the primary diagnostic tools used in three-fourths of cases, and surgical intervention was the primary treatment approach. Albendazole and praziquantel were commonly prescribed postoperatively, and two patients underwent preoperative needle decompression. This systematic review contributes to a better understanding of cerebellar hydatid cysts and guides future research and clinical management of this entity.
小脑包虫囊肿是一种罕见的病变,文献报道的病例有限。鉴于小脑包虫囊肿的可疑指数较低,本系统评价旨在总结当前的诊断和治疗方法。该评价已在国际系统评价前瞻性注册库(PROSPERO)注册,注册号为CRD42023437853。本研究遵循系统评价和Meta分析的首选报告项目(PRISMA-P)报告指南。2023年6月27日,两名独立研究人员检索了PubMed、Scopus和谷歌学术数据库。我们纳入了1965年至2022年发表的15项研究,包括12例病例报告和3个病例系列。对报告的小脑包虫囊肿病例(9名女性和7名男性)进行的汇总分析显示,平均年龄为24±20岁。大多数病例报告于土耳其医院(n = 8)。观察到的主要体征和症状为头痛(10例,62.5%)、共济失调步态(9例,56.25%)和视觉障碍(9例,56.25%)。从症状出现到就诊的时间各不相同,大多数患者在头三个月内就医。左小脑半球是囊肿最常见的部位(6例,37.5%),经常观察到第四脑室受压。计算机断层扫描(CT)和磁共振成像(MRI)是四分之三病例中使用的主要诊断工具,手术干预是主要的治疗方法。阿苯达唑和吡喹酮通常在术后使用,两名患者接受了术前针吸减压。本系统评价有助于更好地了解小脑包虫囊肿,并指导该疾病未来的研究和临床管理。