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以紫胶为基础的食物生物活性化合物传递系统。

Shellac-based delivery systems for food bioactive compounds.

机构信息

Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, China-Canada Joint Lab of Food Nutrition and Health, Beijing Technology and Business University (BTBU), Beijing 100048, China.

Institute of Agricultural Processing Research, Ningbo Academy of Agricultural Sciences, Ningbo 315040, China.

出版信息

Int J Biol Macromol. 2024 Jun;271(Pt 2):132623. doi: 10.1016/j.ijbiomac.2024.132623. Epub 2024 Jun 6.

Abstract

Shellac is a natural resin featuring some attractive properties such as amphiphilicity, pH responsiveness, biocompatibility, and biodegradability. There has been increasing interest in employing shellac for controlled delivery of food bioactive compounds. This review outlines the recent advances in different types of shellac-based delivery systems, including nanoparticles, zein-shellac particles, hydrogels, nanofibers, and nanomicelles. The preparation method, formation mechanism, structure, and delivery performance are investigated. These systems could improve the stability and shelf-life of bioactive compounds, allow for targeted release at the small intestine or colon site, and increase bioavailability. The deficiencies and challenges of each of the systems are also discussed. The promising results in this review could guide future trends in more efficient shellac-based delivery platforms for functional food applications.

摘要

紫胶是一种具有独特性质的天然树脂,如两亲性、pH 响应性、生物相容性和生物降解性。越来越多的人对利用紫胶来控制食物生物活性化合物的释放感兴趣。本综述概述了不同类型的紫胶基输送系统的最新进展,包括纳米粒子、玉米醇溶蛋白-紫胶颗粒、水凝胶、纳米纤维和纳米胶束。研究了它们的制备方法、形成机制、结构和输送性能。这些系统可以提高生物活性化合物的稳定性和保质期,允许在小肠或结肠部位进行靶向释放,并提高生物利用度。还讨论了每种系统的缺陷和挑战。本综述中的有前途的结果可以指导未来更有效的基于紫胶的功能性食品应用输送平台的发展趋势。

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