Bertoletti Antonio
Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.
J Viral Hepat. 2024 Dec;31 Suppl 2:43-55. doi: 10.1111/jvh.13962. Epub 2024 Jun 6.
Hepatitis B virus (HBV) is an ancient virus that has evolved unique strategies to persist as a chronic infection in humans. Here, I summarize the innate and adaptive features of the HBV-host interaction, and I discuss how different profiles of antiviral immunity cannot be predicted only on the basis of virological and clinical parameters.
乙型肝炎病毒(HBV)是一种古老的病毒,它已进化出独特的策略,以便在人类中持续存在并形成慢性感染。在此,我总结了HBV与宿主相互作用的固有和适应性特征,并讨论了如何不能仅基于病毒学和临床参数来预测不同的抗病毒免疫情况。